Evidence map›Paper›PMID 20171099›Full record

ArticleBioorganic & medicinal chemistry letters2010

Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine.

Colin K Skepper, Doralyn S Dalisay, Tadeusz F Molinski

Open access · greenAbstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Synthesis of 2Beilstein journal of organic chemistry · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Colin K SkepperDepartment of Chemistry and Biochemistry, San Diego, La Jolla, CA 92093, USA.
Doralyn S Dalisay
Tadeusz F Molinski
University of Montana · US

Funding

Antifungals from Marine Invertebrates--AIDS AdjuvantsR01AI039987 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOLINSKI, TADEUSZ F · 1997 to 2010
$2.9M
Natural Products for Treatment of Emergent AIDS-Related PathogensR01AI100776 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOLINSKI, TADEUSZ F · 2012 to 2016
$1.9M
ANTIFUNGALS FROM MARINE INVERTEBRATES--AIDS ADJUVANTSR21AI039987 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI MOLINSKI, TADEUSZ F. · 1996 to 1996
–
NIAID NIH HHS AI 039987NIAID NIH HHS R01 AI039987NIAID NIH HHS R01 AI100776
6 · The paper itself

Abstract

Analogues of the antifungal marine natural product (E)-dysidazirine were prepared and evaluated in broth ro-dilution assays against a panel of fungal pathogens. A simple structure-activity relationship was developed which provides insight into the mechanism of action of long-chain 2H-azirine carboxylates.

Indexed as

Antifungal AgentsAzirinesCarboxylic AcidsEstersMicrobial Sensitivity TestsAntifungal AgentsAzirinesCarboxylic AcidsdysidazirineEsters

Identifiers

PMID20171099
PMCPMC2834865
OpenAlexW1996364522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.