ReviewCurrent opinion in immunology2010
Transcriptional regulation of NKT cell development and homeostasis.
Review in Current opinion in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Virtual Memory CD8Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022Review
- The transcription factor BCL-6 controls early development of innate-like T cells.Nature immunology · 2020Article
- Eomes transcription factor is required for the development and differentiation of invariant NKT cells.Communications biology · 2019Article
- The Role of Autophagy in iNKT Cell Development.Frontiers in immunology · 2018Review
- The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation.Frontiers in immunology · 2018Article
- Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Advances in immunology · 2016Review
- Orchestration of invariant natural killer T cell development by E and Id proteins.Critical reviews in immunology · 2015Review
- Roles of TRAF3 in T cells: many surprises.Cell cycle (Georgetown, Tex.) · 2015Review
- The differential roles of mTOR, ERK, and JNK pathways in invariant natural killer T-cell function and survival.Inflammation · 2014Article
- TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells.The Journal of experimental medicine · 2013Article
- Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions.Nature reviews. Immunology · 2013Review
- The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy.Oncoimmunology · 2012Article
- Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2012Review
- PLZF Controls the Expression of a Limited Number of Genes Essential for NKT Cell Function.Frontiers in immunology · 2012Article
- Essential role of Mediator subunit Med1 in invariant natural killer T-cell development.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Review
- Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Alternative memory in the CD8 T cell lineage.Trends in immunology · 2011Review
- Epigenetic reduction in invariant NKT cells following in utero vitamin D deficiency in mice.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Transcriptional control of invariant NKT cell development.Immunological reviews · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
NKT cells comprise a distinct T cell subset that acquires effector function during development and prior to antigen exposure. NKT cells are of limited antigen specificity but possess the ability to be recruited into an immune response without the need for further differentiation or proliferation and thus may be considered to function as memory cells or as part of the innate immune system. Although the development and maturation of NKT cells share some similarities with conventional T cell populations, many transcriptional regulators and signaling molecules are known to be uniquely required for NKT cell development. Recently, new transcription factors that specify NKT lineage and effector function and novel roles for previously identified transcriptional regulators in the differentiation of the NKT cell population have been discovered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.