ReviewClinical and experimental nephrology2010
Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension.
Review in Clinical and experimental nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- The immune regulatory role of lymphangiogenesis in kidney disease.Journal of translational medicine · 2024Review
- Article
- Amplification of Salt-Sensitive Hypertension and Kidney Damage by Immune Mechanisms.American journal of hypertension · 2021Review
- Y Chromosome, Hypertension and Cardiovascular Disease: Is Inflammation the Answer?International journal of molecular sciences · 2019Review
- Immune mechanisms of salt-sensitive hypertension and renal end-organ damage.Nature reviews. Nephrology · 2019Review
- Novel adaptive and innate immunity targets in hypertension.Pharmacological research · 2017Review
- Inflammation and hypertension: new understandings and potential therapeutic targets.Current hypertension reports · 2015Review
- Infiltrating immune cells in the kidney in salt-sensitive hypertension and renal injury.American journal of physiology. Renal physiology · 2014Review
- Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure.Hypertension (Dallas, Tex. : 1979) · 2013Article
- Stress-dependent hypertension and the role of T lymphocytes.Experimental physiology · 2012Review
- Renal inflammation, autoimmunity and salt-sensitive hypertension.Clinical and experimental pharmacology & physiology · 2012Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review examines the participation of immunocompetent cells that accumulate in tubulointerstitial areas of the kidney in the pathogenesis of sodium-sensitive hypertension. Tubulointerstitial inflammation is a universal feature in experimental models of sodium-sensitive hypertension, and the suppression of inflammation and its constant companions, oxidative stress and renal angiotensin II activity, ameliorates or prevents hypertension. Human studies also support the association between renal inflammation and hypertension. The proinflammatory effects of a high sodium diet and the mechanisms by which renal inflammation induces sodium retention are discussed. It is suggested that autoimmune reactivity may play a role in the development and maintenance of renal inflammation in hypertensive states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.