ArticlePloS one2010
Circadian plasticity in photoreceptor cells controls visual coding efficiency in Drosophila melanogaster.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- A one-day journey to the suburbs: circadian clock in the Drosophila visual system.The FEBS journal · 2025Review
- Horizontal-cell like Dm9 neurons inFrontiers in molecular neuroscience · 2024Article
- Roles of peripheral clocks: lessons from the fly.FEBS letters · 2022Review
- CRY-dependent plasticity of tetrad presynaptic sites in the visual system of Drosophila at the morning peak of activity and sleep.Scientific reports · 2020Article
- One Actor, Multiple Roles: The Performances of Cryptochrome inFrontiers in physiology · 2020Review
- Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back.International journal of molecular sciences · 2018Review
- Circadian Rhythms in Visual Responsiveness in the Behaviorally Arrhythmic Drosophila Clock Mutant ClkJournal of biological rhythms · 2017Article
- Cryptochrome Is a Regulator of Synaptic Plasticity in the Visual System ofFrontiers in molecular neuroscience · 2017Article
- Circadian Regulation of Synaptic Plasticity.Biology · 2016Review
- Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress.Aging cell · 2015Article
- Mmp1 processing of the PDF neuropeptide regulates circadian structural plasticity of pacemaker neurons.PLoS genetics · 2014Article
- Sleep, clocks, and synaptic plasticity.Trends in neurosciences · 2014Review
- Fly cryptochrome and the visual system.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Glia-related circadian plasticity in the visual system of Diptera.Frontiers in physiology · 2013Article
- Article
- Peripheral circadian rhythms and their regulatory mechanism in insects and some other arthropods: a review.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2012Review
- Roles for class IIA phosphatidylinositol transfer protein in neurotransmission and behavioral plasticity at the sensory neuron synapses of Caenorhabditis elegans.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the fly Drosophila melanogaster, neuronal plasticity of synaptic terminals in the first optic neuropil, or lamina, depends on early visual experience within a critical period after eclosion. The current study revealed two additional and parallel mechanisms involved in this type of synaptic terminal plasticity. First, an endogenous circadian rhythm causes daily oscillations in the volume of photoreceptor cell terminals. Second, daily visual experience precisely modulates the circadian time course and amplitude of the volume oscillations that the photoreceptor-cell terminals undergo. Both mechanisms are separable in their molecular basis. We suggest that the described neuronal plasticity in Drosophila ensures continuous optimal performance of the visual system over the course of a 24 h-day. Moreover, the sensory system of Drosophila cannot only account for predictable, but also for acute, environmental changes. The volumetric changes in the synaptic terminals of photoreceptor cells are accompanied by circadian and light-induced changes of presynaptic ribbons as well as extensions of epithelial glial cells into the photoreceptor terminals, suggesting that the architecture of the lamina is altered by both visual exposure and the circadian clock. Clock-mutant analysis and the rescue of PER protein rhythmicity exclusively in all R1-6 cells revealed that photoreceptor-cell plasticity is autonomous and sufficient to control visual behavior. The strength of a visually guided behavior, the optomotor turning response, co-varies with synaptic-terminal volume oscillations of photoreceptor cells when elicited at low light levels. Our results show that behaviorally relevant adaptive processing of visual information is performed, in part, at the level of visual input level.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.