Evidence map›Paper›PMID 20169116›Full record

ArticleInternational journal of pediatrics2010

T-lymphocyte subsets in apparently healthy nigerian children.

Emmanuel Oni Idigbe, Rosemary A Audu, Edna O Iroha, Adebola O Akinsulie, Edamisan Olusoji Temiye, Veronica C Ezeaka, Ifedayo M O Adetifa, Adesola Z Musa, Joseph Onyewuche, Sylvester U Ikondu

Abstract read
In one paragraph

Article in International journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emmanuel Oni IdigbeHuman Virology Laboratory, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Rosemary A Audu
Edna O Iroha
Adebola O Akinsulie
Edamisan Olusoji Temiye
Veronica C Ezeaka
Ifedayo M O Adetifa
Adesola Z Musa
Joseph Onyewuche
Sylvester U Ikondu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population studies showed that there are differences in T-lymphocytes subpopulation of normal children in different regions, and reference values in an area might be different from another. This study compared the values in our population with CDC and WHO reference values. Blood samples from 279 healthy, HIV-negative children <12 years of age were analysed for complete blood count, CD3+, CD4+, CD8+ counts and percentages. Except for CD8%, mean values for all parameters measured significantly decreased with age. CD4+ counts were higher in females than males, P < .05. Using the WHO criteria, 15.9% of subjects had low total lymphocyte count and 20.6% had low CD4 count. Children <3 years had median CD4% lower than WHO normal values. Our median CD4+ counts correlated with CDC values. Values used by WHO in infants are higher than ours. We suggest that our children be assessed using CDC reference values which correlate with ours.

Identifiers

PMID20169116
PMCPMC2821635

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.