ArticleClinical ophthalmology (Auckland, N.Z.)2010
Antiviral selection in the management of acute retinal necrosis.
Article in Clinical ophthalmology (Auckland, N.Z.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 39 citations in OpenAlex.
- Successful treatment with repeated dexamethasone implant injections for recurrent macular edema after acute retinal necrosis.Journal of ophthalmic inflammation and infection · 2022Article
- Management Strategies of Acute Retinal Necrosis: Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Valacyclovir as Initial Treatment for Acute Retinal Necrosis: A Pharmacokinetic Modeling and Simulation Study.Current eye research · 2017Article
- Efficacy of Oral Valacyclovir Treatment in a Case with Acute Retinal Necrosis.Turkish journal of ophthalmology · 2017Article
- A case report of Epstein-Barr virus-associated retinal vasculitis: successful treatment using only acyclovir therapy.International medical case reports journal · 2016Article
- Clinical manifestation of self-limiting acute retinal necrosis.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Efficacy and necessity of prophylactic vitrectomy for acute retinal necrosis syndrome.International journal of ophthalmology · 2012Article
- Sudden unilateral visual loss in a healthy adult female.Journal of postgraduate medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no consensus on the optimal antiviral regimen in the management of acute retinal necrosis, a disease caused by herpetic viruses with devastating consequences for the eye. The current gold standard is based on retrospective case series. Because the incidence of disease is low, few well-designed, randomized trials have evaluated treatment dosage and duration. Newer oral antiviral agents are emerging as alternatives to high-dose intravenous acyclovir, avoiding the need for inpatient intravenous treatment. Drug resistance is uncommon but may also be difficult to identify. Antiviral drugs have few side effects, but special attention needs to be paid to patients who have underlying renal disease, are pregnant or are immunocompromised.
Indexed as
Identifiers
20169044PMC2819764W2051463899What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.