ArticleAddictive behaviors2010
Effect of methamphetamine dependence on everyday functional ability.
Article in Addictive behaviors, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 95 citations in OpenAlex.
- Abbreviated Goal Management Training Shows Preliminary Evidence as a Neurorehabilitation Tool for HIV-associated Neurocognitive Disorders among Substance Users.The Clinical neuropsychologist · 2016Trial
- Methamphetamine dependent individuals show attenuated brain response to pleasant interoceptive stimuli.Drug and alcohol dependence · 2013Trial
- The Protective Role of Collective Efficacy Against Illicit Drug Availability at the Street Level: A Longitudinal Analysis.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- Trail Making Test performance in early abstinence from methamphetamine: human evidence for a drug-associated Parkinsonian-like phenotype.Frontiers in psychiatry · 2026Article
- Temporal changes in cognitive functions and associated factors among stimulant users: a 12-month, prospective study.Scientific reports · 2025Article
- Methamphetamine produces behavioral flexibility deficits that are attenuated by COX-2 inhibition in both male and female rats.Addiction neuroscience · 2025Article
- The Association between Childhood Trauma on Executive Functioning and Treatment Outcomes among Individuals with Methamphetamine Use Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Individuals recently abstinent from methamphetamine show selective cognitive and behavioral differences when compared to age-matched controls.Frontiers in psychiatry · 2025Article
- Methamphetamine abuse impairs sequential working memory.Frontiers in psychiatry · 2024Article
- Modeling methamphetamine use disorder and relapse in animals: short- and long-term epigenetic, transcriptional., and biochemical consequences in the rat brain.Neuroscience and biobehavioral reviews · 2023Review
- Narcotics Anonymous members in recovery from methamphetamine use disorder.The American journal on addictions · 2023Article
- Computational models of exploration and exploitation characterise onset and efficacy of treatment in methamphetamine use disorder.Addiction biology · 2022Article
- Training and transfer effects of working memory updating training in male abstinent long-term methamphetamine users.Addictive behaviors reports · 2021Article
- Article
- The role of CYP2D in rat brain in methamphetamine-induced striatal dopamine and serotonin release and behavioral sensitization.Psychopharmacology · 2021Article
- Apathy is associated with poorer abstinence self-efficacy in individuals with methamphetamine dependence.Addictive behaviors reports · 2021Article
- Trends in Methamphetamine Use Among Men Who Have Sex with Men in New York City, 2004-2017.AIDS and behavior · 2021Article
- Impulsivity, Emotional Dysregulation and Executive Function Deficits Could Be Associated with Alcohol and Drug Abuse in Eating Disorders.Journal of clinical medicine · 2020Article
- Vocational evaluation and vocational guidance for young people with a history of drug abuse.Work (Reading, Mass.) · 2019Article
- The relationship between impulsivity and methamphetamine use severity in a community sample.Drug and alcohol dependence · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMethamphetamine (METH) is an increasingly popular and highly addictive psychostimulant with a significant impact on public health. Chronic METH exposure has been associated with neurotoxic effects, profound neuropsychological deficits, and impaired quality of life, but few studies have examined the effect of the drug on the ability to carry out everyday activities. We assessed the effect of METH dependence on everyday functioning using the UCSD Performance-Based Skills Assessment (UPSA-2), a performance-based measure designed to evaluate real-life skills.
methodUPSA-2 performance was quantified in 15 currently abstinent individuals with a history of METH dependence and 15 drug-free comparison subjects. The Positive and Negative Syndrome Scale (PANSS) and Wisconsin Card Sorting Task (WCST) were administered to assess psychopathology and executive function.
resultsMETH-dependent participants exhibited significant impairment on the UPSA-2 total score and several UPSA-2 subscales, including comprehension, finance, transportation, communication, and medication management compared to drug-free comparison subjects. Lower UPSA-2 scores were associated with impaired performance on the WCST, higher PANSS scores, and drug use at an earlier age.
conclusionMETH dependence may be associated with decreased everyday functioning ability potentially mediated by frontal cortex dysfunction or the emergence of psychopathology related to chronic drug use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.