Evidence map›Paper›PMID 20166889›Full record

ReviewGrowth factors (Chur, Switzerland)2010

The applied biochemistry of PEDF and implications for tissue homeostasis.

Matthew L Broadhead, S Patricia Becerra, Peter F M Choong, Crispin R Dass

Abstract readReview
In one paragraph

Review in Growth factors (Chur, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Prokaryotic Collagen-Like Proteins as Novel Biomaterials.Frontiers in bioengineering and biotechnology · 2022
    Review
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Protective Effects ofOxidative medicine and cellular longevity · 2018
    Article
  7. Review
  8. Diabetes and Wound Angiogenesis.International journal of molecular sciences · 2017
    Review
  9. Article
  10. Article
  11. Review
  12. Pigment epithelium-derived factor as a multifunctional regulator of wound healing.American journal of physiology. Heart and circulatory physiology · 2015
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew L BroadheadDepartment of Orthopaedics, St Vincent's Hospital, University of Melbourne, Melbourne, Vic., Australia.
S Patricia Becerra
Peter F M Choong
Crispin R Dass
National Institutes of Health · US

Funding

Role of Protein Interactions in Retina Development and FunctionZIAEY000306 · NEI · NATIONAL EYE INSTITUTE · PI BECERRA, S. PATRICIA · 2009 to 2025
$15.6M
Intramural NIH HHS ZIA EY000306
6 · The paper itself

Abstract

Pigment epithelium-derived factor (PEDF) is an endogenously produced glycoprotein with a spectrum of biological roles across diverse pathologies. Recent research has focused on the biochemical properties of PEDF and its associated receptors. This review discusses the recent developments in PEDF biochemistry and how this new knowledge will help progress our understanding of PEDF as a molecular mediator for anti-angiogenesis and -tumorigenesis. Additionally, pathophysiological roles for PEDF in healing and tissue homeostasis are being revealed and our enhanced understanding of the interactions between PEDF and its receptors may yet prove useful in propelling PEDF towards clinical application.

Indexed as

Angiogenesis InhibitorsAntineoplastic AgentsEye ProteinsNerve Growth FactorsSerpinsAnimalsApoptosisDoxorubicinHomeostasisHumansNeoplasmsNeovascularization, PathologicPigment Epithelium-Derived FactorReceptors, NeuropeptideRetinal Pigment EpitheliumSerine Proteinase InhibitorsAngiogenesis InhibitorsAntineoplastic AgentsDoxorubicinEye ProteinsNerve Growth FactorsPigment Epithelium-Derived Factorpigment epithelium-derived factor receptorReceptors, NeuropeptideSerine Proteinase InhibitorsSerpins

Identifiers

PMID20166889
PMCPMC3931573
OpenAlexW2141692468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.