Evidence map›Paper›PMID 20166810›Full record

ReviewTissue engineering. Part B, Reviews2010

Adipose tissue engineering for soft tissue regeneration.

Jennifer H Choi, Jeffrey M Gimble, Kyongbum Lee, Kacey G Marra, J Peter Rubin, James J Yoo, Gordana Vunjak-Novakovic, David L Kaplan

Open access · greenAbstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 255 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Therapeutic potential of adipose tissue in aesthetic medicine.World journal of experimental medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Long term observation ofRegenerative therapy · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jennifer H ChoiDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA.
Jeffrey M Gimble
Kyongbum Lee
Kacey G Marra
J Peter Rubin
James J Yoo
Gordana Vunjak-Novakovic
David L Kaplan
Tufts University · USUniversity of Pittsburgh · USColumbia University · USForest Institute · USLouisiana State University System · US

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
NIBIB NIH HHS P41 EB002520PHS HHS P41
6 · The paper itself

Abstract

Current treatment modalities for soft tissue defects caused by various pathologies and trauma include autologous grafting and commercially available fillers. However, these treatment methods present a number of challenges and limitations, such as donor-site morbidity and volume loss over time. As such, improved therapeutic modalities need to be developed. Tissue engineering techniques offer novel solutions to these problems through development of bioactive tissue constructs that can regenerate adipose tissue in both structure and function. Recently, a number of studies have been designed to explore various methods to engineer human adipose tissue. This review will focus on these developments in the area of adipose tissue engineering for soft tissue replacement. The physiology of adipose tissue and current surgical therapies used to replace lost tissue volume, specifically in breast tissue, are introduced, and current biomaterials, cell sources, and tissue culture strategies are discussed. We discuss future areas of study in adipose tissue engineering.

Indexed as

Adipose TissueAnimalsBiocompatible MaterialsRegenerationTissue Culture TechniquesTissue EngineeringBiocompatible Materials

Identifiers

PMID20166810
PMCPMC2946881
OpenAlexW1995669659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.