ReviewDrugs2010
Pharmacotherapy and weight-loss supplements for treatment of paediatric obesity.
Review in Drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Trial
- Lifestyle intervention improves fitness independent of metformin in obese adolescents.Medicine and science in sports and exercise · 2012 · on this mapTrial
- Pharmacotherapy for the Treatment of Overweight and Obesity in Children, Adolescents, and Young Adults in a Large Health System in the US.Frontiers in endocrinology · 2020Article
- Survey of antiobesity drug prescribing for obese children and young people in UK primary care.BMJ paediatrics open · 2017Article
- Cardiovascular effects of bariatric surgery.Nature reviews. Cardiology · 2016Review
- Pediatric obesity pharmacotherapy: current state of the field, review of the literature and clinical trial considerations.International journal of obesity (2005) · 2016Review
- Bariatric and Metabolic Surgery in Adolescents: a Path to Decrease Adult Cardiovascular Mortality.Current atherosclerosis reports · 2015Review
- Bariatric surgery in adolescents and young adults--safety and effectiveness in a cohort of 345 patients.International journal of obesity (2005) · 2014Article
- Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: rationale, design, and methods.Child and adolescent psychiatry and mental health · 2013Article
- Unlicensed use of metformin in children and adolescents in the UK.British journal of clinical pharmacology · 2012Article
- Pharmacological approaches for management of child and adolescent obesity.Journal of clinical medicine research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity has become the most common paediatric disorder in the developed world. Treatment of obesity in children may include lifestyle interventions, pharmacotherapy and weight-loss supplements. The outcome of lifestyle interventions, which classically include dietary modifications, increased activity and behavioural modifications, remains insufficient and the adjuvant role of pharmacological agents has been proposed. Among the group of weight-loss medications, orlistat is the only pharmaceutical approved by the US FDA for the treatment of overweight and obese adolescents. The role of metformin needs to be established in larger studies and sibutramine remains an experimental product because of its potential adverse events. Weight-loss supplements lack sufficient data supporting their efficacy and safety, even in adults, and cannot be recommended at this time for adolescents. Preliminary data suggest that the use of fibre supplements, such as glucomannan, provides additional weight loss in individuals receiving a lifestyle intervention. No single approach will successfully treat obesity, and lifestyle modification presently remains the main pillar of any intervention aiming at decreasing bodyweight.
Indexed as
Identifiers
20166770What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.