SynthesisThe Cochrane database of systematic reviews2010
Routine intracranial pressure monitoring in acute coma.
Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Routine intracranial pressure monitoring in acute coma.The Cochrane database of systematic reviews · 2015Pooled it
- The effects of intracranial pressure monitoring in patients with traumatic brain injury.PloS one · 2014Pooled it
- Theory of arterial acceleration: implications for transcranial Doppler monitoring in patients with severe traumatic brain injury.Frontiers in physiology · 2025Article
- Intracranial pressure monitoring: Gold standard and recent innovations.World journal of clinical cases · 2019Review
- Coma After Acute Head Injury.Deutsches Arzteblatt international · 2017Review
- Continuous Qualitative Electroencephalography as a Noninvasive Neuromonitor.The Neurohospitalist · 2016Article
- Therapy in pediatric stroke.European journal of pediatrics · 2013Review
- Physiological monitoring of the severe traumatic brain injury patient in the intensive care unit.Current neurology and neuroscience reports · 2013Review
- Critical care management of severe traumatic brain injury in adults.Scandinavian journal of trauma, resuscitation and emergency medicine · 2012Review
- Intracranial Pressure Monitoring: Invasive versus Non-Invasive Methods-A Review.Critical care research and practice · 2012Article
- Multimodal monitoring and neurocritical care bioinformatics.Nature reviews. Neurology · 2011Review
- Intracranial pressure and its surrogates.Intensive care medicine · 2011Article
Corrections and comments
- Updated by
- Update of
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies in traumatic encephalopathy first led to the insight that the damage seen was not just due to direct consequences of the primary injury. A significant, and potentially preventable, contribution to the overall morbidity arose from secondary hypoxic-ischaemic damage. Brain swelling accompanied by raised intracranial pressure (ICP) resulted in inadequate cerebral perfusion with well-oxygenated blood. Detection of raised ICP could be useful in alerting clinicians to the need to improve cerebral perfusion, with consequent reductions in brain injury.
objectivesTo determine whether routine ICP monitoring in all acute cases of severe coma reduces the risk of all-cause mortality or severe disability at final follow-up. SEARCH STRATEGY: We searched the Cochrane Injuries Group's Specialised Register (searched 7 April 2009), CENTRAL (The Cochrane Library 2009, Issue 1), MEDLINE 1950 to March week 4 2009, EMBASE 1980 to week 14 March 2009, CINAHL 1982 to March 2009, ISI Web of Science: Science Citation Index Expanded (SCI-EXPANDED) 1970 to March 2009, Conference Proceedings Citation Index- Science (CPCI-S) 1990 to March 2009, PubMed (searched 7 April 2009, limit; added in last 6 months). The searches were last updated in April 2009. SELECTION CRITERIA: All randomised controlled studies of real-time ICP monitoring by invasive or semi-invasive means in acute coma (traumatic or non-traumatic aetiology) versus no ICP monitoring (that is, clinical assessment of ICP). DATA COLLECTION AND ANALYSIS: Primary outcome measures were all-cause mortality and severe disability at the end of the follow-up period. MAIN
resultsNo studies meeting the selection criteria have been identified to date. AUTHORS'
conclusionsThere are no data from randomised controlled trials that can clarify the role of ICP monitoring in acute coma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.