ArticleInternational journal of diabetes in developing countries2009
Lipid abnormalities in streptozotocin-diabetes: Amelioration by Morus indica L. cv Suguna leaves.
Article in International journal of diabetes in developing countries, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 70 citations in OpenAlex.
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- Beneficial effects of food-medicine homologous herbs for patients with diabetic kidney disease.Frontiers in immunology · 2025Review
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- A pre-clinical study to investigate the anti-diabetic potential ofJournal of diabetes and metabolic disorders · 2023Article
- The Effect of Guisangyou Tea on Abnormal Lipid Metabolism in Mice Induced by High-Fat Diet.Foods (Basel, Switzerland) · 2023Article
- LC-MS-based metabolite profiling of aqueous extract ofIranian journal of basic medical sciences · 2022Article
- Antidiabetic and Antihyperlipidemic Effects of Methanolic Extract of Leaves ofFrontiers in physiology · 2022Article
- Therapeutic Potentials ofJournal of inflammation research · 2021Article
- A novel library of -arylketones as potential inhibitors of α-glucosidase: Their design, synthesis, in vitro and in vivo studies.Scientific reports · 2017Article
- The cardioprotective power of leaves.Archives of medical science : AMS · 2015Article
- Therapeutic effects of stem cell on hyperglycemia, hyperlipidemia, and oxidative stress in alloxan-treated rats.Molecular and cellular biochemistry · 2014Article
- Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.Biochemistry research international · 2012Article
- Influences of crude extract of tea leaves, Camellia sinensis, on streptozotocin diabetic male albino mice.Saudi journal of biological sciences · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo observe the influence of mulberry (Morus indica L. cv Suguna) leaves on lipid abnormalities in STZ-diabetic rats. MATERIALS AND
methodsTreatment with dried mulberry leaf powder for a period of 8 weeks in hyperglycemic and hyperlipidemic STZ-diabetic rats.
resultsMulberry leaves regulated fasting blood glucose, ameliorated the abnormalities in lipid profile as indicated by significant (P<0.01) decrease in serum triglycerides, phospholipids, cholesterol and plasma free fatty acids by 50, 6, 31 and 22% respectively in STZ- diabetic rats compared to diabetic control rats which had significantly (P<0.01) raised levels of triglycerides, phospholipids, cholesterol and free fatty acids than the normal control rats. A marked increase in fecal bile acids (154%) was observed in mulberry treated diabetic rats compared to the diabetic control group indicating conversion of cholesterol to bile acids. In addition, mulberry supplementation significantly lowered LDL-C (67%) and VLDL-C (44%) levels and increased HDL-C (53%) and also decreased atherogenic index (58%) significantly when compared to the diabetic control group.
conclusionBesides the diabetic rats, mulberry leaves affected lipid profile in normal rats also indicating hypolipidemic effect as a result of the synergistic action of bioactive compounds.
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