ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
Presynaptic GABA(B) receptors regulate experience-dependent development of inhibitory short-term plasticity.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- GABA corelease guides the functional maturation of glycinergic synapses in an auditory sound localization circuit.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Long-latency auditory evoked responses across species show increased amplitude during early life.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Article
- Lateralized local circuit tuning in female mouse auditory cortex.Neuroscience research · 2025Article
- Does age protect against loss of tonotopy after acute deafness in adulthood?Frontiers in cellular neuroscience · 2024Article
- A Redundant Cortical Code for Speech Envelope.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Developmental depression-to-facilitation shift controls excitation-inhibition balance.Communications biology · 2022Article
- Auditory processing remains sensitive to environmental experience during adolescence in a rodent model.Nature communications · 2022Article
- Keeping the Balance: GABABrain sciences · 2022Review
- Development of Auditory Cortex Circuits.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Differential Short-Term Plasticity of PV and SST Neurons Accounts for Adaptation and Facilitation of Cortical Neurons to Auditory Tones.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Regulation of auditory plasticity during critical periods and following hearing loss.Hearing research · 2020Review
- Single-nucleus RNA sequencing of mouse auditory cortex reveals critical period triggers and brakes.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Preserving Inhibition during Developmental Hearing Loss Rescues Auditory Learning and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Discrimination of Motion Direction in a Robot Using a Phenomenological Model of Synaptic Plasticity.Computational intelligence and neuroscience · 2019Article
- Sensory overamplification in layer 5 auditory corticofugal projection neurons following cochlear nerve synaptic damage.Nature communications · 2018Article
- Developmental deprivation-induced perceptual and cortical processing deficits in awake-behaving animals.eLife · 2018Article
- Homeostatic plasticity in neural development.Neural development · 2018Review
- A Critical Role of Inhibition in Temporal Processing Maturation in the Primary Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Inhibitory circuit gating of auditory critical-period plasticity.Nature neuroscience · 2018Article
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3 authors.
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Abstract
Short-term changes in synaptic gain support information processing throughout the CNS, yet we know little about the developmental regulation of such plasticity. Here we report that auditory experience is necessary for the normal maturation of synaptic inhibitory short-term plasticity (iSTP) in the auditory cortex, and that presynaptic GABA(B) receptors regulate this development. Moderate or severe hearing loss was induced in gerbils, and iSTP was characterized by measuring inhibitory synaptic current amplitudes in response to repetitive stimuli. We reveal a profound developmental shift of iSTP from depressing to facilitating after the onset of hearing. Even moderate hearing loss prevented this shift. This iSTP change was mediated by a specific class of inhibitory interneurons, the low-threshold spiking cells. Further, using paired recordings, we reveal that presynaptic GABA(B) receptors at interneuron-pyramidal connections regulate iSTP in an experience-dependent manner. This novel synaptic mechanism may support the emergence of mature temporal processing in the auditory cortex.
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