ArticleThe American journal on addictions
Age at regular drinking, clinical course, and heritability of alcohol dependence in the San Francisco family study: a gender analysis.
Article in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Sex differences in insular cortex function in persistent alcohol drinking despite aversion in mice.Molecular psychiatry · 2026Article
- Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders.The Journal of clinical investigation · 2024Review
- Genetic factors associated with suicidal behaviors and alcohol use disorders in an American Indian population.Molecular psychiatry · 2024Article
- The clinical course of antisocial behaviors in men and women of three racial groups.Journal of psychiatric research · 2022Article
- Effects of genetic risk for alcohol dependence and onset of regular drinking on the progression to alcohol dependence: A polygenic risk score approach.Drug and alcohol dependence · 2022Article
- Gender Differences among Sardinians with Alcohol Use Disorder.Journal of clinical medicine · 2021Article
- Common genetic substrates of alcohol and substance use disorder severity revealed by pleiotropy detection against GWAS catalog in two populations.Addiction biology · 2021Article
- Interaction of chronic intermittent ethanol and repeated stress on structural and functional plasticity in the mouse medial prefrontal cortex.Neuropharmacology · 2021Article
- Adaptation and Pilot Testing of the Women's Recovery Group for Young Adults (WRG-YA).Alcoholism treatment quarterly · 2021Article
- The role of sex in the persistent effects of adolescent alcohol exposure on behavior and neurobiology in rodents.International review of neurobiology · 2021Review
- Prevalence, Demographic, and Clinical Correlates of Comorbid Depressive Symptoms in Chinese Psychiatric Patients With Alcohol Dependence.Frontiers in psychiatry · 2020Article
- Genetic loci for alcohol-related life events and substance-induced affective symptoms: indexing the "dark side" of addiction.Translational psychiatry · 2019Article
- Indexing the 'dark side of addiction': substance-induced affective symptoms and alcohol use disorders.Addiction (Abingdon, England) · 2019Article
- Sex differences in alcohol self-administration and relapse-like behavior in Long-Evans rats.Pharmacology, biochemistry, and behavior · 2017Article
- Alcohol drinking during adolescence increases consumptive responses to alcohol in adulthood in Wistar rats.Alcohol (Fayetteville, N.Y.) · 2017Article
- Clinical characteristics of alcohol combined with other substance use disorders in an American Indian community sample.Drug and alcohol dependence · 2016Article
- Differences in polysubstance use among youth in the child welfare system: toward a better understanding of the highest-risk teens.Child abuse & neglect · 2016Article
- The clinical course of DSM-5 alcohol use disorders in young adult native and Mexican Americans.The American journal on addictions · 2015Article
- Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.Scientific reports · 2015Article
- Gender differences in the relationship between alcohol use and depressive symptoms in St. Petersburg, Russia.Journal of addiction research & therapy · 2012Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
We examined gender differences in age of onset, clinical course, and heritability of alcohol dependence in 2,524 adults participating in the University of California San Francisco (UCSF) family study of alcoholism. Men were significantly more likely than women to have initiated regular drinking during adolescence. Onset of regular drinking was not found to be heritable but was found to be significantly associated with a shorter time to onset of alcohol dependence. A high degree of similarity in the sequence of alcohol-related life events was found between men and women, however, men experienced alcohol dependence symptoms at a younger age and women had a more rapid clinical course. Women were found to have a higher heritability estimate for alcohol dependence (h(2)= .46) than men (h(2)= .32). These findings suggest that environmental factors influencing the initiation of regular drinking rather than genetic factors associated with dependence may in part underlie some of the gender differences seen in the prevalence of alcohol dependence in this population. (Am J Addict 2010;00:1-10).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.