ArticleThe Journal of cell biology1991
Identification of sequences necessary for the association of cardiac myosin subunits.
Article in The Journal of cell biology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.Biophysical journal · 1998Article
- Mapping of the actomyosin interfaces.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes.The Journal of clinical investigation · 1993Article
- Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains.The Journal of cell biology · 1992Article
- Probing myosin light chain 1 structure with monoclonal antibodies.Journal of muscle research and cell motility · 1992Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
To begin to understand the nature of myosin subunit assembly, we determined the region of a vertebrate sarcomeric myosin heavy chain required for binding of light chain 1. We coexpressed in Escherichia coli segments of the rat alpha cardiac myosin heavy chain which spanned the carboxyl terminus of subfragment 1 and the amino terminus of subfragment 2 with a full-length rat cardiac myosin light chain 1. A 16 amino acid region of the myosin heavy chain (residues 792-808) was shown to be required for myosin light chain 1 binding in an immunoprecipitation assay.
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Registered trials
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