ArticleCroatian medical journal2010
Interactions between genetic variants in glucose transporter type 9 (SLC2A9) and dietary habits in serum uric acid regulation.
Article in Croatian medical journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts.BMJ (Clinical research ed.) · 2018Pooled it
- The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications.Frontiers in pharmacology · 2024Review
- Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans.Nutrients · 2019Article
- Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.Clinical kidney journal · 2016Article
- Gout: a review of nonmodifiable and modifiable risk factors.Rheumatic diseases clinics of North America · 2014Review
- Article
- Characterization of in vitro cultured myoblasts isolated from duck (Anas platyrhynchos) embryo.Cytotechnology · 2011Article
- Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.PloS one · 2011Article
- Uric acid: the past decade.Croatian medical journal · 2010Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimTo investigate possible interactions between genetic variants in glucose transporter type 9 (SLC2A9) gene and dietary habits in serum uric acid regulation.
methodsParticipants for this study were recruited from two isolated Croatian island communities of Vis (n=918) and Korcula (n=898). Three single nucleotide polymorphisms (SNP) from the SLC2A9 gene (rs1014290, rs6449213, rs737267) were correlated with dietary habits and uric acid.
resultsA significant decrease in uric acid levels was recorded with increasing consumption of milk, sour cream, duck and turkey, and eggs. The only significant interaction was found between potato consumption and rs737267 and a near-significant interaction was found between soft drinks and rs1014290 (interaction P=0.068). Increased consumption of soft drinks interacting with the TT genotype at rs1014290 increased serum uric acid. No significant interactions were observed between food products consumption and rs6449213.
conclusionThere is a certain extent of interaction between SLC2A9 and dietary patterns in serum uric acid determination. The metabolic effect of soft drinks seems to be determined by the underlying genotype of rs1014290.
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