ArticleIndian journal of dermatology2009
Chronic autoimmune urticaria: where we stand?
Article in Indian journal of dermatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Autologous serum therapy reduces the symptoms and antihistamine burden in patients with chronic urticaria.Postepy dermatologii i alergologii · 2023Article
- The efficacy and safety of herbal combination of Unani Medicine in chronic urticaria: A randomized, controlled study.Journal of traditional and complementary medicine · 2021Article
- Review
- Economic Burden of the Inadequate Management of Allergic Rhinitis and Urticaria in Asian Countries Based on the GA²LEN Model.Allergy, asthma & immunology research · 2018Article
- OSMR gene effect on the pathogenesis of chronic autoimmune Urticaria via the JAK/STAT3 pathway.Molecular medicine (Cambridge, Mass.) · 2018Article
- Omalizumab efficacy in cases of chronic spontaneous urticaria is not explained by the inhibition of sera activity in effector cells.Scientific reports · 2017Article
- Differential expression of microRNAs and their possible roles in patients with chronic idiopathic urticaria and active hives.Allergy & rhinology (Providence, R.I.) · 2017Article
- An unusual migratory polycyclic eruption after administration of prostaglandin E in a neonate.JAAD case reports · 2016Article
- Comparative Study of Positive Versus Negative Autologous Serum Skin Test in Chronic Spontaneous Urticaria and its Treatment Outcome.North American journal of medical sciences · 2016Article
- Association Between PTPN22 Polymorphisms and IgE Responses to Staphylococcal Superantigens in Chronic Urticaria.Allergy, asthma & immunology research · 2015Article
- Autologous serum skin test as an indicator of chronic autoimmune urticaria in a tertiary care hospital in South India.Indian dermatology online journal · 2014Article
- Vitamin d supplements improve urticaria symptoms and quality of life in chronic spontaneous urticaria patients: a prospective case-control study.Dermato-endocrinology · 2014Article
- Autologous serum skin test as a diagnostic aid in chronic idiopathic urticaria.ISRN dermatology · 2013Article
- Clinical and investigative assessment of patients with positive versus negative autologous serum skin test: a study of 80 South Indian patients.Indian journal of dermatology · 2012Article
- Management of chronic urticaria in Asia: 2010 AADV consensus guidelines.Asia Pacific allergy · 2012Article
- Chronic urticaria.Indian journal of dermatology · 2011Article
- Vitamin D supplements improve urticaria symptoms and quality of life in chronic spontaneous urticaria patients: A prospective case-control study.Dermato-endocrinologyArticle
- Chronic Spontaneous Urticaria: An Etiopathogenic Study.Indian journal of dermatologyArticle
- Weekly injection of histaglobulin produces long-term remission in chronic urticaria: A prospective clinical study.Indian journal of pharmacologyArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well-recognized that 30-40% of chronic idiopathic urticaria is autoimmune in nature. Chronic autoimmune urticaria is caused by anti-FcepsilonRI and less frequently, by anti-IgE autoantibodies that lead to mast cell and basophil activation, thereby giving rise to the release of histamine and other proinflammatory mediators. Activation of the classical complement pathway and formation of C5a are important in dermal mast cell activation. C5a is also a neutrophil and eosinophil chemoattractant. Chronic autoimmune urticaria has been found to be associated with autoimmune thyroid disease. The autologous serum skin test is used as a screening test for chronic autoimmune urticaria and has a sensitivity and specificity of about 70 and 80%, respectively. The current gold standard diagnostic test is the basophil histamine release assay. The treatment of chronic autoimmune urticaria, as in chronic idiopathic urticaria, is with H1 antihistamines. Oral corticosteroids may be used during acute flares. Refractory cases have been shown to respond to cyclosporine and other immunomodulators. The prevalence of chronic autoimmune urticaria in Singapore is similar to that reported in Western countries at about 42%. The presence of thyroid autoimmunity appears to be higher than reported, with 22.5% of patients with chronic idiopathic urticaria here, exhibiting presence of thyroid autoantibodies.
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Registered trials
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