ArticleFrontiers in molecular neuroscience2009
Cellular transport and membrane dynamics of the glycine receptor.
Article in Frontiers in molecular neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 46 citations in OpenAlex.
- Synaptic vs. Non-Synaptic Glycine Receptors: Physiological Role and Implications in Alzheimer's Disease Pathology.International journal of molecular sciences · 2026Review
- Long-term potentiation of glycinergic synapses by semi-natural stimulation patterns during tonotopic map refinement.Scientific reports · 2020Article
- News about non-secretory exocytosis: mechanisms, properties, and functions.Journal of molecular cell biology · 2019Review
- mGluR5/ERK signaling regulated the phosphorylation and function of glycine receptor α1ins subunit in spinal dorsal horn of mice.PLoS biology · 2019Article
- Article
- Lack of the Actin Capping Protein, Eps8, Affects NMDA-Type Glutamate Receptor Function and Composition.Frontiers in molecular neuroscience · 2018Article
- Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- In Vivo Measurement of Glycine Receptor Turnover and Synaptic Size Reveals Differences between Functional Classes of Motoneurons in Zebrafish.Current biology : CB · 2017Article
- Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7.Journal of cell science · 2015Article
- Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation.Nature communications · 2014Article
- Gephyrin: a master regulator of neuronal function?Nature reviews. Neuroscience · 2014Review
- Article
- Genetic deficiency of GABA differentially regulates respiratory and non-respiratory motor neuron development.PloS one · 2013Article
- Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Targeting inhibitory neurotransmission in tinnitus.Brain research · 2012Review
- Specific sets of intrinsic and extrinsic factors drive excitatory and inhibitory circuit formation.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2012Review
- Splice-specific glycine receptor binding, folding, and phosphorylation of the scaffolding protein gephyrin.The Journal of biological chemistry · 2012Article
- Expression and subcellular distribution of gephyrin in non-neuronal tissues and cells.Histochemistry and cell biology · 2012Article
- Mixed inhibitory synaptic balance correlates with glutamatergic synaptic phenotype in cerebellar unipolar brush cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Homeostatic strengthening of inhibitory synapses is mediated by the accumulation of GABA(A) receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regulation of synaptic transmission is essential to tune individual-to-network neuronal activity. One way to modulate synaptic strength is to regulate neurotransmitter receptor numbers at postsynaptic sites. This can be achieved either through plasma membrane insertion of receptors derived from intracellular vesicle pools, a process depending on active cytoskeleton transport, or through surface membrane removal via endocytosis. In parallel, lateral diffusion events along the plasma membrane allow the exchange of receptor molecules between synaptic and extrasynaptic compartments, contributing to synaptic strength regulation. In recent years, results obtained from several groups studying glycine receptor (GlyR) trafficking and dynamics shed light on the regulation of synaptic GlyR density. Here, we review (i) proteins and mechanisms involved in GlyR cytoskeletal transport, (ii) the diffusion dynamics of GlyR and of its scaffolding protein gephyrin that control receptor numbers, and its relationship with synaptic plasticity, and (iii) adaptative changes in GlyR diffusion in response to global activity modifications, as a homeostatic mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.