ArticleJournal of neurolinguistics2010
The Genetic Basis of Thought Disorder and Language and Communication Disturbances in Schizophrenia.
Article in Journal of neurolinguistics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The Epidemiology and Associated Phenomenology of Formal Thought Disorder: A Systematic Review.Schizophrenia bulletin · 2015Pooled it
- Parental communication and psychosis: a meta-analysis.Schizophrenia bulletin · 2014Pooled it
- PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies.Journal of molecular neuroscience : MN · 2012Pooled it
- No foreign language effect in Schizotypy: Evidence from German-English bilinguals.Schizophrenia research. Cognition · 2026Review
- Exploring the interplay between language use and cognitive function in schizophrenia spectrum disorders: Insights from patients, first degree relatives, and healthy controls.Schizophrenia research. Cognition · 2026Review
- Brain Markers of Resilience to Psychosis in High-Risk Individuals: A Systematic Review and Label-Based Meta-Analysis of Multimodal MRI Studies.Brain sciences · 2025Review
- Predicting new onset thought disorder in early adolescence with optimized deep learning implicates environmental-putamen interactions.medRxiv : the preprint server for health sciences · 2023Article
- Perspective on clinical high-risk for psychosis in Africa.Frontiers in psychiatry · 2023Article
- Language abnormalities in schizophrenia: binding core symptoms through contemporary empirical evidence.Schizophrenia (Heidelberg, Germany) · 2022Review
- Assessing the dimensionality of scores derived from the Revised Formal Thought Disorder Self-Report Scale in schizotypy.PloS one · 2022Article
- Thought Disorder as a Neglected Dimension in Schizophrenia.Alpha psychiatry · 2022Review
- Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.Journal of neurodevelopmental disorders · 2021Article
- Language as a biomarker for psychosis: A natural language processing approach.Schizophrenia research · 2020Review
- QSAR modeling and docking analysis of D2 receptor with known olanzapine derivatives.Bioinformation · 2020Article
- Cognitive profiles in childhood and adolescence differ between adult psychotic and affective symptoms: a prospective birth cohort study.Psychological medicine · 2018Article
- Rethinking Thought Disorder.Schizophrenia bulletin · 2017Article
- Thought Disorder in Schizophrenia and Bipolar Disorder Probands, Their Relatives, and Nonpsychiatric Controls.Schizophrenia bulletin · 2017Article
- Can RDoC Help Find Order in Thought Disorder?Schizophrenia bulletin · 2017Review
- A QSAR model of Olanzapine derivatives as potential inhibitors for 5-HT2A Receptor.Bioinformation · 2017Article
- Neural circuit of verbal humor comprehension in schizophrenia - an fMRI study.NeuroImage. Clinical · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Thought disorder as well as language and communication disturbances are associated with schizophrenia and are over-represented in clinically unaffected relatives of schizophrenics. All three kinds of dysfunction involve some element of deviant verbalizations, most notably, semantic anomalies. Of particular importance, thought disorder characterized primarily by deviant verbalizations has a higher recurrence in relatives of schizophrenic patients than schizophrenia itself. These findings suggest that deviant verbalizations may be more penetrant expressions of schizophrenia susceptibility genes than schizophrenia. This paper reviews the evidence documenting the presence of thought, language and communication disorders in schizophrenic patients and in their first-degree relatives. This familial aggregation potentially implicates genetic factors in the etiology of thought disorder, language anomalies, and communication disturbances in schizophrenia families. We also present two examples of ways in which thought, language and communication disorders can enrich genetic studies, including those involving schizophrenia.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.