Evidence map›Paper›PMID 20161679›Full record

ArticleFuture virology2009

Dengue virus markers of virulence and pathogenicity.

Rebeca Rico-Hesse

Open access · greenAbstract read
In one paragraph

Article in Future virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Patterns, Drivers, and Challenges of Vector-Borne Disease Emergence.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2020
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. The importance of hematopoietic progenitor cells in dengue.Therapeutic advances in hematology · 2012
    Article
  11. Issues related to recent dengue vaccine development.Tropical medicine and health · 2011
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rebeca Rico-HesseDepartment of Virology & Immunology, Southwest Foundation for Biomedical Research, 7620 NW Loop 410, San Antonio, TX 78245, USA.
Texas Biomedical Research Institute · US

Funding

Dengue Virus Determinants of Virulence and TransmissionR01AI050123 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI RICO-HESSE, REBECCA R · 2001 to 2009
$3.6M
NIAID NIH HHS R01 AI050123
6 · The paper itself

Abstract

The increased spread of dengue fever and its more severe form, dengue hemorrhagic fever, have made the study of the mosquito-borne dengue viruses that cause these diseases a public health priority. Little is known about how or why the four different (serotypes 1-4) dengue viruses cause pathology in humans only, and there have been no animal models of disease to date. Therefore, there are no vaccines or antivirals to prevent or treat infection and mortality rates of dengue hemorrhagic fever patients can reach up to 20%. Cases occur mainly in tropical zones within developing countries worldwide, and control measures have been limited to the elimination of the mosquito vectors. Thus, it is imperative that we develop new methods of studying dengue virus pathogenicity. This article presents new approaches that may help us to understand dengue virus virulence and the specific mechanisms that lead to dengue fever and severe disease.

Identifiers

PMID20161679
PMCPMC2821058
OpenAlexW2152220525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.