ArticleMacromolecular rapid communications2009
Design and Synthesis of Fast-Degrading Poly(anhydride-esters).
Article in Macromolecular rapid communications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Impact of Polymer Degradation on Cellular Behavior in Tissue Engineering.Bioprinting (Amsterdam, Netherlands) · 2025Article
- Polyanhydride Microcapsules Exhibiting a Sharp pH Transition at Physiological Conditions for Instantaneous Triggered Release.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Poly(anhydride-ester) gemcitabine: Synthesis and particle engineering of a high payload hydrolysable polymeric drug for cancer therapy.Journal of controlled release : official journal of the Controlled Release Society · 2021Article
- Modulating lysosomal pH: a molecular and nanoscale materials design perspective.Journal of life sciences (Westlake Village, Calif.) · 2020Article
- Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma.Journal for immunotherapy of cancer · 2019Article
- Phenolic Acid-based Poly(anhydride-esters) as Antioxidant Biomaterials.Macromolecular bioscience · 2016Article
- Salicylic Acid-Based Polymers for Guided Bone Regeneration Using Bone Morphogenetic Protein-2.Tissue engineering. Part A · 2015Article
- Poly(anhydride-ester) and poly(N-vinyl-2-pyrrolidone) blends: salicylic acid-releasing blends with hydrogel-like properties that reduce inflammation.Macromolecular bioscience · 2015Article
- Synthesis and Characterization of a Poly(ethylene glycol)-Poly(simvastatin) Diblock Copolymer.RSC advances · 2014Article
- Stimuli-responsive copolymer solution and surface assemblies for biomedical applications.Chemical Society reviews · 2013Review
- Formulation of salicylate-based poly(anhydride-ester) microspheres for short- and long-term salicylic acid delivery.Polymer bulletin (Berlin, Germany) · 2013Article
- Tunable drug release profiles from salicylate-based poly(anhydride-ester) matrices using small molecule admixtures.Journal of bioactive and compatible polymers · 2012Article
- PolyMorphine: an innovative biodegradable polymer drug for extended pain relief.Journal of controlled release : official journal of the Controlled Release Society · 2012Article
- Stability of a salicylate-based poly(anhydride-ester) to electron beam and gamma radiation.Polymer degradation and stability · 2011Article
- Storage Stability Study of Salicylate-based Poly(anhydride-esters).Polymer degradation and stability · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fast-degrading, salicylate-based poly(anhydride-esters) were designed to degrade and release the active component, salicylic acid (SA), within 1 week. The polymer degradation was enhanced by using shorter or oxygen-containing aliphatic chains. A copolymer of diglycolic acid was also made with a salicylate-based diacid for comparison of polymer properties, including SA release. Both methods resulted in polyanhydrides with molecular weights ranging from 14 500 to 27 800 Da and displayed glass transition temperatures near physiological conditions, namely 33-40 degrees C. the homo- and copolymers completely degraded within one week releasing the chemically incorporated SA.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.