ArticleProteomics. Clinical applications2009
Sources of Urinary Proteins and their Analysis by Urinary Proteomics for the Detection of Biomarkers of Disease.
Article in Proteomics. Clinical applications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review: Urine Biomarker Discovery for Inflammatory Bowel Disease Diagnosis.International journal of molecular sciences · 2023Pooled it
- Comparison of SERS Substrates in Direct Analysis of Urine Samples for Detection of Albuminuria: Relatively Large Gold Nano-Spheroids Outperform Gold Nanorods on Gold Film.International journal of molecular sciences · 2026Article
- Review
- Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson's disease.Nature neuroscience · 2025Article
- Article
- SDS Electrophoresis on Gradient Polyacrylamide Gels as a Semiquantitative Tool for the Evaluation of Proteinuria.Diagnostics (Basel, Switzerland) · 2023Article
- Urinary biomarkers for amyotrophic lateral sclerosis: candidates, opportunities and considerations.Brain communications · 2023Review
- Urinary Proteomic Profile of Arterial Stiffness Is Associated With Mortality and Cardiovascular Outcomes.Journal of the American Heart Association · 2022Article
- Urinary Dipstick Is Not Reliable as a Screening Tool for Albuminuria in the Emergency Department-A Prospective Cohort Study.Diagnostics (Basel, Switzerland) · 2022Article
- Current applications of capillary electrophoresis-mass spectrometry for the analysis of biologically important analytes in urine (2017 to mid-2021): A review.Journal of separation science · 2022Review
- Urinary immunoglobulins in viral diagnosis: An overview.The Indian journal of medical research · 2022Review
- Voided urine test to diagnose prostate cancer: Preliminary report.CytoJournal · 2021Article
- Urinary Biomarkers for Neurodegenerative Diseases.Experimental neurobiology · 2020Review
- Development and validation of hybrid Brillouin-Raman spectroscopy for non-contact assessment of mechano-chemical properties of urine proteins as biomarkers of kidney diseases.BMC nephrology · 2020Article
- Impact of heavy rains of 2018 in western Japan: disaster-induced health outcomes among the population of Innoshima Island.Heliyon · 2020Article
- Monitoring cellulose oxidation for protein immobilization in paper-based low-cost biosensors.Mikrochimica acta · 2020Article
- Molecular determinants of nephron vascular specialization in the kidney.Nature communications · 2019Article
- Simple Tip-Based Sample Processing Method for Urinary Proteomic Analysis.Analytical chemistry · 2019Article
- Leptospiral 3-hydroxyacyl-CoA dehydrogenase as an early urinary biomarker of leptospirosis.Heliyon · 2018Article
- Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study.Disease markers · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Renal disorders account for a substantial fraction of the budget for health care in many countries. Proteinuria is a frequent manifestation in afflicted patients, but the origin of the proteins varies based on the nature of the disorder. The emerging field of urinary proteomics has the potential to replace kidney biopsy as the diagnostic procedure of choice for patients with some glomerular forms of renal disease. To fully realize this potential, it is vital to understand the basis for the urinary excretion of protein in physiological and pathological conditions. In this review, we discuss the structure of the nephron, the functional unit of the kidney, and the process by which proteins/peptides enter the urine. We discuss several aspects of proteinuria that impact the proteomic analysis of urine of patients with renal diseases.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.