ArticleJournal of neurodevelopmental disorders2009
Anxiety disorders in children with williams syndrome, their mothers, and their siblings: implications for the etiology of anxiety disorders.
Article in Journal of neurodevelopmental disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Anxiety Disorders in Williams Syndrome Contrasted with Intellectual Disability and the General Population: A Systematic Review and Meta-Analysis.Journal of autism and developmental disorders · 2017Pooled it
- Anxiety and obsessive-compulsive disorder (OCD) in adults with CHARGE syndrome.Journal of neurodevelopmental disorders · 2026Article
- Anxiety in Young Children with Williams Syndrome: A Longitudinal Study.Children (Basel, Switzerland) · 2025Article
- Internalising and Externalising Symptoms and Their Association with the Family Environment in Young Children with Williams Syndrome: A Longitudinal Study.Children (Basel, Switzerland) · 2023Article
- Short Report: Lack of Diurnal Variation in Salivary Cortisol Is Linked to Sleep Disturbances and Heightened Anxiety in Adolescents with Williams Syndrome.Behavioral sciences (Basel, Switzerland) · 2023Article
- Article
- Williams syndrome.Nature reviews. Disease primers · 2021Review
- Williams Syndrome, Human Self-Domestication, and Language Evolution.Frontiers in psychology · 2019Article
- Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome.Journal of autism and developmental disorders · 2018Article
- Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes.Journal of autism and developmental disorders · 2017Article
- Predictors of specific phobia in children with Williams syndrome.Journal of intellectual disability research : JIDR · 2016Article
- Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome.Journal of autism and developmental disorders · 2016Article
- The Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Review
- Symmetrical Dose-Dependent DNA-Methylation Profiles in Children with Deletion or Duplication of 7q11.23.American journal of human genetics · 2015Article
- Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands.Intractable & rare diseases research · 2015Article
- Characterizing associations and dissociations between anxiety, social, and cognitive phenotypes of Williams syndrome.Research in developmental disabilities · 2014Article
- Psychiatric symptoms in boys with fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder.Research in developmental disabilities · 2014Article
- Regionally specific increased volume of the amygdala in Williams syndrome: evidence from surface-based modeling.Human brain mapping · 2014Article
- Diurnal cortisol profile in Williams syndrome in novel and familiar settings.American journal on intellectual and developmental disabilities · 2013Article
- Factor structure of the Children's Behavior Questionnaire in children with Williams syndrome.Journal of autism and developmental disorders · 2012Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo determine the prevalence of anxiety disorders in children with Williams syndrome (WS), their sibling closest in age, and their mothers and to examine the predictors of anxiety in these groups.
methodsThe prevalence of anxiety disorders was assessed and compared to that in the general population.
resultsChildren with WS had a significantly higher prevalence of specific phobia, generalized anxiety disorder (GAD), and separation anxiety in comparison to children in the general population. While mothers had a higher prevalence of GAD than population controls, the excess was accounted for by mothers who had onset after the birth of their WS child. The siblings had rates similar to the general population.
conclusionsThis pattern of findings suggests the presence of a gene in the WS region whose deletion predisposes to anxiety disorders. It is also worthwhile to investigate relations between genes deleted in WS and genes previously implicated in anxiety disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.