ArticleTetrahedron letters2009
An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis.
Article in Tetrahedron letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity.Molecules (Basel, Switzerland) · 2021Article
- Assessments of tumor metabolism with CEST MRI.NMR in biomedicine · 2019Review
- Solid-Phase-Supported Approach for the Preparation of Bioresponsive and Multifunctional MRI Probes.Organic letters · 2019Article
- Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI.Magnetic resonance in medicine · 2017Article
- Diamagnetic Imaging Agents with a Modular Chemical Design for Quantitative Detection of β-Galactosidase and β-Glucuronidase Activities with CatalyCEST MRI.Bioconjugate chemistry · 2016Article
- A CatalyCEST MRI Contrast Agent that Can Simultaneously Detect Two Enzyme Activities.Chembiochem : a European journal of chemical biology · 2016Article
- Detecting enzyme activities with exogenous MRI contrast agents.Chemistry (Weinheim an der Bergstrasse, Germany) · 2014Review
- Detection of in vivo enzyme activity with CatalyCEST MRI.Magnetic resonance in medicine · 2014Article
- A catalyCEST MRI contrast agent that detects the enzyme-catalyzed creation of a covalent bond.Journal of the American Chemical Society · 2013Article
- Strategies for the preparation of bifunctional gadolinium(III) chelators.Current organic synthesis · 2011Article
- On the Synthesis of 1,4,7-Tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane.Tetrahedron letters · 2011Article
- Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.Methods in molecular biology (Clifton, N.J.) · 2011Article
- An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis.Tetrahedron letters · 2009Article
- A single diamagnetic catalyCEST MRI contrast agent that detects cathepsin B enzyme activity by using a ratio of two CEST signals.Contrast media & molecular imagingArticle
- A review of responsive MRI contrast agents: 2005-2014.Contrast media & molecular imagingReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
An amine-derivatized DOTA has been used to modify the surface of a polymeric support for conventional Solid Phase Peptide Synthesis (SPPS) following standard Fmoc chemistry methods. This methodology was used to synthesize a peptide-DOTA conjugate that was demonstrated to be a PARACEST MRI contrast agent. Therefore, this synthesis methodology can facilitate Fmoc SPPS of molecular imaging contrast agents.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.