ArticleFuture neurology2009
Developmental hearing loss disrupts synaptic inhibition: implications for auditory processing.
Article in Future neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Predisposing Factors for Congenital Hearing Loss: A Comprehensive Systematic Review.Turkish archives of otorhinolaryngology · 2026Article
- Innervation Pattern of Inhibitory Projection Neurons in the Bird Sound Localization Circuit.The Journal of comparative neurology · 2026Article
- Hearing and early life adversity: effects of developmental stress on sensory processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Central auditory tests reveal deficits in HIV treatment.Frontiers in public health · 2026Article
- Expression of group II mGluRs in the inferior colliculus, medial geniculate body, and auditory cortex increases with age.Neuroscience · 2025Article
- P1-N1-P2 Cortical Auditory Evoked Potentials in Chronic Unilateral Acquired Conductive Hearing Loss in Adults.The journal of international advanced otology · 2024Article
- Neural hyperactivity and altered envelope encoding in the central auditory system: Changes with advanced age and hearing loss.Hearing research · 2024Review
- Impact of Prematurity on Auditory Processing in Children.Pathophysiology : the official journal of the International Society for Pathophysiology · 2023Article
- Increased Central Auditory Gain and Decreased Parvalbumin-Positive Cortical Interneuron Density in theBiological psychiatry global open science · 2023Article
- Auditory Deprivation during Development Alters Efferent Neural Feedback and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Developmental changes in electrophysiological properties of auditory cortical neurons in theJournal of neurophysiology · 2023Article
- The role of GABAFrontiers in endocrinology · 2023Review
- Peripheral Fragile X messenger ribonucleoprotein is required for the timely closure of a critical period for neuronal susceptibility in the ventral cochlear nucleus.Frontiers in cellular neuroscience · 2023Article
- Sound source localization patterns and bilateral cochlear implants: Age at onset of deafness effects.PloS one · 2022Article
- Visuo-Acoustic Stimulation's Role in Synaptic Plasticity: A Review of the Literature.International journal of molecular sciences · 2021Review
- Hearing loss and brain plasticity: the hyperactivity phenomenon.Brain structure & function · 2021Review
- Dynamics of the fragile X mental retardation protein correlates with cellular and synaptic properties in primary auditory neurons following afferent deprivation.The Journal of comparative neurology · 2021Article
- Early Sensory Deprivation Leads to Differential Inhibitory Changes in the Striatum During Learning.Frontiers in neural circuits · 2021Article
- Auditory Sensory Gating in Children With Cochlear Implants: A P50-N100-P200 Study.Frontiers in neuroscience · 2021Article
- Linking anatomical and physiological markers of auditory system degeneration with behavioral hearing assessments in a mouse (Mus musculus) model of age-related hearing loss.Neurobiology of aging · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Hearing loss during development leads to central deficits that persist even after the restoration of peripheral function. One key class of deficits is due to changes in central inhibitory synapses, which play a fundamental role in all aspects of auditory processing. This review focuses on the anatomical and physiological alterations of inhibitory connections at several regions within the central auditory pathway following hearing loss. Such aberrant inhibitory synaptic function may be linked to deficits in encoding binaural and spectral cues. Understanding the cellular changes that occur at inhibitory synapses following hearing loss may provide specific loci that can be targeted to improve function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.