ArticleExpert review of respiratory medicine2009
Pathophysiology, management and treatment of smoke inhalation injury.
Article in Expert review of respiratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 167 citations in OpenAlex.
- Inhaled anticoagulation regimens for the treatment of smoke inhalation-associated acute lung injury: a systematic review.Critical care medicine · 2014Pooled it
- Continuous extracorporeal hyperoxygenation therapy reduces carbon monoxide half-life time in a carbon monoxide-poisoned pig model: a feasibility study.Scientific reports · 2026Article
- Scheduled Bronchoscopy with Nebulized Heparin and N-Acetylcysteine in Burn Patients with Inhalation Injury: A Randomized Trial.European burn journal · 2026Article
- Review
- Excessive dynamic airway collapse: A condition behind the veil.World journal of methodology · 2026Review
- Epidemiology of microbiological findings in the lower respiratory tract in mechanically ventilated patients with and without inhalation injury.Frontiers in cellular and infection microbiology · 2026Observational
- Ferroptosis in smoke inhalation injury: from mechanisms to potential therapeutic targets.Frontiers in cell and developmental biology · 2026Review
- Human adipose-derived stem cell exosomes alleviate human respiratory system-related cells damaged by exposure to SOJournal of biosciences · 2025Article
- Evidence for Hydroxocobalamin in Cyanide Toxicity Caused by Smoke Inhalation: An Updated Systematic Review.Emergency medicine international · 2025Review
- Article
- Quantitative proteome and lysine succinylome characterization of zinc chloride smoke-induced lung injury in mice.Heliyon · 2024Article
- Examination of Pediatric Burn Incidence and the Impact of Social Determinants of Health in Florida.Cureus · 2024Article
- Screening and Phasewise Management of Burn Injuries.Cureus · 2024Review
- An atypical airway cast.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Frequency, complications, and mortality of inhalation injury in burn patients: A systematic review and meta-analysis protocol.PloS one · 2024Article
- Article
- An international RAND/UCLA expert panel to determine the optimal diagnosis and management of burn inhalation injury.Critical care (London, England) · 2023Article
- Article
- The Alleviation of LPS-Induced Murine Acute Lung Injury by GSH-Mediated PEGylated Artesunate Prodrugs.Frontiers in pharmacology · 2022Article
- The role and therapeutic potential of gut microbiome in severe burn.Frontiers in cellular and infection microbiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Smoke inhalation injury continues to increase morbidity and mortality in burn patients in both the third world and industrialized countries. The lack of uniform criteria for the diagnosis and definition of smoke inhalation injury contributes to the fact that, despite extensive research, mortality rates have changed little in recent decades. The formation of reactive oxygen and nitrogen species, as well as the procoagulant and antifibrinolytic imbalance of alveolar homeostasis, all play a central role in the pathogenesis of smoke inhalation injury. Further hallmarks include massive airway obstruction owing to cast formation, bronchospasm, the increase in bronchial circulation and transvascular fluid flux. Therefore, anticoagulants, antioxidants and bronchodilators, especially when administered as an aerosol, represent the most promising treatment strategies. The purpose of this review article is to provide an overview of the pathophysiological changes, management and treatment options of smoke inhalation injury based on the current literature.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.