ReviewCancer imaging : the official publication of the International Cancer Imaging Society2010
CT perfusion in oncology: how to do it.
Review in Cancer imaging : the official publication of the International Cancer Imaging Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.
- Quantitative CT perfusion imaging in patients with pancreatic cancer: a systematic review.Abdominal radiology (New York) · 2022Pooled it
- Article
- Dual-energy CT biomarkers for predicting the efficacy of TACE combined with lenvatinib and immune checkpoint inhibitors in unresectable HCC.European radiology experimental · 2026Article
- AI-based denoising improves image quality in HCC volume perfusion CT without affecting Milan classification.BMC medical imaging · 2026Article
- Diagnostically competitive performance of a physiology-informed generative multi-task network for contrast-free CT perfusion.Frontiers in human neuroscience · 2026Article
- CECT and CT Perfusion Correlation with Pathological Differentiation of Pharyngeal and Laryngeal Cancers: Study from a Tertiary Care Center in Northeast India.The Indian journal of radiology & imaging · 2025Article
- Decreased attenuation difference between non-contrast and portal-venous phases of CT predicts the ultrasonography-unspecified adnexal torsion.Insights into imaging · 2025Article
- Current trends in the characterization and monitoring of vascular response to cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Review
- Automated Quantitative Analysis of CT Perfusion to Classify Vascular Phenotypes of Pancreatic Ductal Adenocarcinoma.Cancers · 2024Article
- Assessment of Computed Tomography Perfusion Research Landscape: A Topic Modeling Study.Tomography (Ann Arbor, Mich.) · 2023Review
- Comparison of CT- and MRI-Based Quantification of Tumor Heterogeneity and Vascularity for Correlations with Prognostic Biomarkers and Survival Outcomes: A Single-Center Prospective Cohort Study.Bioengineering (Basel, Switzerland) · 2023Article
- Dynamic contrast-enhanced (DCE) imaging: state of the art and applications in whole-body imaging.Japanese journal of radiology · 2022Review
- Dynamic contrast-enhanced MRI in oncology: how we do it.La Radiologia medica · 2020Review
- Impact of spectral body imaging in patients suspected for occult cancer: a prospective study of 503 patients.European radiology · 2020Article
- Can Dynamic Contrast-Enhanced CT Quantify Perfusion in a Stimulated Muscle of Limited Size? A Rat Model.Clinical orthopaedics and related research · 2020Article
- Iterative reconstruction algorithm improves the image quality without affecting quantitative measurements of computed tomography perfusion in the upper abdomen.European journal of radiology open · 2020Article
- Dynamic Contrast-Enhanced CT in Patients with Pancreatic Cancer.Diagnostics (Basel, Switzerland) · 2016Review
- Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer.Diagnostics (Basel, Switzerland) · 2016Article
- Lung radiofrequency and microwave ablation: a review of indications, techniques and post-procedural imaging appearances.The British journal of radiology · 2015Review
- Correlation between CT perfusion and clinico-pathological features in prostate cancer: a prospective study.Medical science monitor : international medical journal of experimental and clinical research · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Robust technique and accurate data analysis are required for reliable computed tomography perfusion (CTp) imaging. Multislice CT is required for high temporal resolution scanning; 16-slice (or 64-slice) scanners are preferred for adequate volume coverage. After tumour localization, the volume of CTp imaging has to be positioned to include the maximum visible area of the tumour and an adequate arterial vessel. Dynamic scans at high temporal resolution (at least 1-s gantry rotation time) are performed to visualize the first pass of contrast agent within the tumour; repeated scans with low temporal resolution can be planned for late enhancement assessment. A short bolus of conventional iodinated contrast agent, preferably with high iodine concentration, is power injected at a high flow rate (>4 ml/s) in the antecubital vein. The breath-hold technique is required for CTp imaging of the chest and upper abdomen to avoid respiratory motion; free breathing is adequate for CTp imaging of the head, neck and pelvis. Using dedicated software, a region of interest (ROI) has to be placed in an adequate artery (as arterial input) to obtain density-time curves; according to different kinetic models, colour maps of different CTp parameters are generated and generally overlaid on CT images. Additional ROIs can be positioned in the tumour, and in all other parts of the CTp volume, to obtain the values of the CTp parameters within the ROI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.