Evidence map›Paper›PMID 20159344›Full record

ReviewThe Psychiatric clinics of North America2010

Genetics of obsessive-compulsive disorder.

Gerald Nestadt, Marco Grados, Jack F Samuels

Abstract readReview
In one paragraph

Review in The Psychiatric clinics of North America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  7. Article
  8. Article
  9. Article
  10. DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders.Journal of autism and developmental disorders · 2021
    Article
  11. Article
  12. Article
  13. Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Sex differences in the genetic architecture of obsessive-compulsive disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gerald NestadtDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Meyer 113, 600 North Wolfe Street, Baltimore, MD 21287, USA. gnestadt@jhmi.edu
Marco Grados
Jack F Samuels

Funding

FAMILY STUDY OF OBSESSIVE COMPULSIVE DISORDERR01MH050214 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 1995 to 2005
$6.6M
OCD Collaborative Genetics Association StudyR01MH071507 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 2007 to 2010
$6.5M
NCRR NIH HHS RR00052NIMH NIH HHS R01 MH050214NIMH NIH HHS R01 MH071507NIMH NIH HHS R01-MH-071507NIMH NIH HHS R01-MH-50214
6 · The paper itself

Abstract

Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.

Indexed as

EnvironmentGenetic Association StudiesGenetic LinkageHumansObsessive-Compulsive DisorderPhenotype

Identifiers

PMID20159344
PMCPMC2824902

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.