ReviewThe Journal of allergy and clinical immunology2010
The role of pharmacogenomics in improving the management of asthma.
Review in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02360696 (Predictors of Clinical Response to Montelukast in Children With Functional Dyspepsia), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predictors of Clinical Response to Montelukast in Children With Functional Dyspepsia
Who cites it
15 citing papers in PubMed.
- Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026Review
- Asthma/Rhinitis (The United Airway) and Allergy: Chicken or Egg; Which Comes First?Journal of clinical medicine · 2020Review
- Glucocorticoid-Induced Transcription Factor 1 (GLCCI1) Variant Impacts the Short-Term Response to Intranasal Corticosteroids in Chinese Han Patients with Seasonal Allergic Rhinitis.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Article
- Prototype of a Standards-Based EHR and Genetic Test Reporting Tool Coupled with HL7-Compliant Infobuttons.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018Article
- Physicians' pharmacogenomics information needs and seeking behavior: a study with case vignettes.BMC medical informatics and decision making · 2017Article
- Pharmacogenetics of Asthma.Indian journal of pediatrics · 2015Article
- Admixture of beneficial and unfavourable variants of GLCCI1 and FCER2 in Roma samples can implicate different clinical response to corticosteroids.Molecular biology reports · 2014Article
- Cellular mechanism underlying formaldehyde-stimulated Cl- secretion in rat airway epithelium.PloS one · 2013Article
- Asthma treatment outcome in children is associated with vascular endothelial growth factor A (VEGFA) polymorphisms.Molecular diagnosis & therapy · 2012Article
- Advancing asthma care: the glass is only half full!The Journal of allergy and clinical immunology · 2011Review
- Advances in pediatric asthma in 2010: addressing the major issues.The Journal of allergy and clinical immunology · 2011Review
- Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma.The Journal of allergy and clinical immunology · 2010Article
- Immunological and genetic aspects of asthma and allergy.Journal of asthma and allergy · 2010Article
- Beta-Adrenergic Agonists.Pharmaceuticals (Basel, Switzerland) · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
There is a large amount of interindividual variability in both therapeutic and adverse responses to asthma therapies. Genetic variability can account for 50% to 60% of this variability. Pharmacogenomics holds out the promise of allowing clinicians to prospectively choose therapies that have the greatest likelihood to be effective for individual patients and to avoid those that might have a high likelihood of producing adverse effects. In this article we review the principles of pharmacogenomic investigation. We explore the data developed from the early pharmacogenomic studies with the most common asthma therapies. Furthermore, we explore the potential use of pharmacogenomics, as well as caveats in interpreting such information.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.