Evidence map›Paper›PMID 20158898›Full record

ReviewJournal of translational medicine2010

Lasers, stem cells, and COPD.

Feng Lin, Steven F Josephs, Doru T Alexandrescu, Famela Ramos, Vladimir Bogin, Vincent Gammill, Constantin A Dasanu, Rosalia De Necochea-Campion, Amit N Patel, Ewa Carrier and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of translational medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00130377 (Biological Cell Therapy for the Treatment of Patients With Thoracic & Cardiovascular Disease), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00130377 phase2 / phase3unknown statusnot on this map

Biological Cell Therapy for the Treatment of Patients With Thoracic & Cardiovascular Disease

TypeinterventionalSponsorAmit N. Patel MD MSRan2002 to 2020Enrolled1,000ConditionsCardiovascular System Diseases (& [Cardiac])Armscell therapy
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Efficacy of Low-Level Laser Therapy in a Rabbit Model of Rhinosinusitis.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Low-Level Laser Therapy: Potential and Complications.Journal of lasers in medical sciences · 2021
    Review
  13. Review
  14. Review
  15. Evaluation of Laser Effects on the Human Body After Laser Therapy.Journal of lasers in medical sciences · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Biological effects of low level laser therapy.Journal of lasers in medical sciences · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Feng LinEntest BioMedical, San Diego, CA, USA.
Steven F Josephs
Doru T Alexandrescu
Famela Ramos
Vladimir Bogin
Vincent Gammill
Constantin A Dasanu
Rosalia De Necochea-Campion
Amit N Patel
Ewa Carrier
David R Koos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, non-thermal intervention that has the potential to modulate regenerative processes is worthy of attention when searching for novel methods of augmenting stem cell-based therapies. Here we discuss the use of LLL irradiation as a "photoceutical" for enhancing production of stem cell growth/chemoattractant factors, stimulation of angiogenesis, and directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autologous stem cells, as well as post-mobilization directing of stem cells will be discussed.

Indexed as

Low-Level Light TherapyStem CellsAnimalsCell DifferentiationCell ProliferationClinical Trials as TopicHumansIntercellular Signaling Peptides and ProteinsNeovascularization, PhysiologicPulmonary Disease, Chronic ObstructiveStem Cell TransplantationIntercellular Signaling Peptides and Proteins

Identifiers

PMID20158898
PMCPMC2830167

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.