ArticleFaraday discussions2010
Hierarchical coarse-graining strategy for protein-membrane systems to access mesoscopic scales.
Article in Faraday discussions, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure.Journal of chemical theory and computation · 2023Article
- A survey of multiscale modeling: Foundations, historical milestones, current status, and future prospects.AIChE journal. American Institute of Chemical Engineers · 2021Article
- Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations.Scientific reports · 2019Article
- Organizing membrane-curving proteins: the emerging dynamical picture.Current opinion in structural biology · 2018Review
- Biophysics of membrane curvature remodeling at molecular and mesoscopic lengthscales.Journal of physics. Condensed matter : an Institute of Physics journal · 2018Article
- Long-Range Organization of Membrane-Curving Proteins.ACS central science · 2017Article
- The mesoscopic membrane with proteins (MesM-P) model.The Journal of chemical physics · 2017Article
- Multiscale simulations of protein-facilitated membrane remodeling.Journal of structural biology · 2016Review
- Atomic-level description of protein-lipid interactions using an accelerated membrane model.Biochimica et biophysica acta · 2016Review
- Atomic Modeling of an Immature Retroviral Lattice Using Molecular Dynamics and Mutagenesis.Structure (London, England : 1993) · 2015Article
- Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution.The Journal of membrane biology · 2015Review
- Membrane tension controls the assembly of curvature-generating proteins.Nature communications · 2015Article
- α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry.Journal of the American Chemical Society · 2014Article
- Linear aggregation of proteins on the membrane as a prelude to membrane remodeling.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Effects of ATP and actin-filament binding on the dynamics of the myosin II S1 domain.Biophysical journal · 2013Article
- Protein-mediated transformation of lipid vesicles into tubular networks.Biophysical journal · 2013Article
- Understanding the role of amphipathic helices in N-BAR domain driven membrane remodeling.Biophysical journal · 2013Article
- A Hybrid Approach for Highly Coarse-grained Lipid Bilayer Models.Journal of chemical theory and computation · 2013Article
- Exploring the dynamics of four RNA-dependent RNA polymerases by a coarse-grained model.The journal of physical chemistry. B · 2012Article
- Membrane binding and self-association of the epsin N-terminal homology domain.Journal of molecular biology · 2012Article
Corrections and comments
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3 authors.
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Abstract
An overall multiscale simulation strategy for large scale coarse-grain simulations of membrane protein systems is presented. The protein is modeled as a heterogeneous elastic network, while the lipids are modeled using the hybrid analytic-systematic (HAS) methodology, where in both cases atomistic level information obtained from molecular dynamics simulation is used to parameterize the model. A feature of this approach is that from the outset liposome length scales are employed in the simulation (i.e., on the order of 1/2 a million lipids plus protein). A route to develop highly coarse-grained models from molecular-scale information is proposed and results for N-BAR domain protein remodeling of a liposome are presented.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.