ArticleVirus genes2010
Human alpha and beta papillomaviruses use different synonymous codon profiles.
Article in Virus genes, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Translational regulation of human papillomavirus mRNAs in carcinogenesis: old questions and new insights.Frontiers in cell and developmental biology · 2025Review
- Why HPV16? Why, now, HPV42? How the discovery of HPV42 in rare cancers provides an opportunity to challenge our understanding about the transition between health and disease for common members of the healthy microbiota.FEMS microbiology reviews · 2024Review
- Article
- Mutation Profiles, Glycosylation Site Distribution and Codon Usage Bias of Human Papillomavirus Type 16.Viruses · 2021Article
- HPV disease transmission protection and control.Microbial cell (Graz, Austria) · 2016Review
- Cancer, Warts, or Asymptomatic Infections: Clinical Presentation Matches Codon Usage Preferences in Human Papillomaviruses.Genome biology and evolution · 2015Article
- Papillomaviruses: Viral evolution, cancer and evolutionary medicine.Evolution, medicine, and public health · 2015Review
- Role of the host restriction factor APOBEC3 on papillomavirus evolution.Virus evolution · 2015Article
- Role of genomic and proteomic tools in the study of host-virus interactions and virus evolution.Indian journal of virology : an official organ of Indian Virological Society · 2013Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Human papillomaviruses use rare codons relative to their hosts. It has been theorized that this is a mechanism to allow the virus to escape immune surveillance. In the present study, we examined the codings of four major genes of 21 human alpha (mucosatropic) viruses and 16 human beta (cutaneous-tropic) viruses. We compared the codon usage of different genes from a given papillomavirus and also the same genes from different papillomaviruses. Our data showed that codon usage was not always uniform between two genes of a given papillomavirus or between the same genes of papillomaviruses from different genera. We speculate as to why this might be and conclude that codon usage in the papillomaviruses may not only play a role in facilitating escape from immune surveillance but may also underlie some of the unanswered questions in the papillomavirus field.
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Registered trials
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