Evidence map›Paper›PMID 20157415›Full record

ArticleKorean journal of ophthalmology : KJO2010

Subconjunctival bevacizumab as an adjunct to trabeculectomy in eyes with refractory glaucoma: a case series.

Jin Young Choi, Jaewan Choi, Yeon-Deok Kim

Abstract readCase Reports
In one paragraph

Article in Korean journal of ophthalmology : KJO, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Short-Term Results of Sutureless Scleral Tunnel Trabeculectomy Using Adjunctive Topical Bevacizumab.Medical hypothesis, discovery & innovation ophthalmology journal · 2018
    Article
  4. Article
  5. Neovascular Glaucoma.Developments in ophthalmology · 2016
    Review
  6. Article
  7. Anti-VEGF Agents and Glaucoma Filtering Surgery.Journal of ophthalmic & vision research · 2013
    Article
  8. Post-trabeculectomy topical bevacizumab preventing bleb failure: a preliminary study.Journal of ocular biology, diseases, and informatics · 2012
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jin Young ChoiHanGil Eye Hospital, Incheon, Korea.
Jaewan Choi
Yeon-Deok Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective observational case series study included 6 eyes of 6 consecutive glaucomatous patients. Each patient underwent trabeculectomy with mitomycin C, and received a 1.25 mg of subconjunctival bevacizumab injection at completion of the trabeculectomy. Study eyes included two with neovascular glaucoma, three with uveitic glaucoma, and one with secondary glaucoma following vitrectomy. All eyes had undergone failed glaucoma laser/surgical treatment or an intraocular surgical procedure. Intraocular pressure (IOP) at the following postoperative visits: preoperative, 1 week, 1 month, 2 months, 3 months, and 6 months, was measured. We also evaluated postoperative bleb findings and complications. IOP measured at each visit was 37.5+/-14.4 mmHg, 6.2+/-3.4 mmHg, 8.3+/-7.2 mmHg, 12.0+/-4.4 mmHg, 10.8+/-3.1 mmHg, and 12.2+/-3.3 mmHg, respectively, for each visit. All eyes had functioning blebs with normal IOP at postoperative 6 months with no additional IOP-lowering medication.

Indexed as

AdultAgedAngiogenesis InhibitorsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabConjunctivaFemaleGlaucomaGlaucoma, NeovascularHumansInjections, IntraocularMaleMiddle AgedProspective StudiesTrabeculectomyAngiogenesis InhibitorsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabVascular Endothelial Growth Factor AAngiogenesis InhibitorsGlaucomaMonoclonal antibodiesTrabeculectomyVascular endothelial growth factors

Identifiers

PMID20157415
PMCPMC2817825

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.