ReviewNature reviews. Urology2010
Treatment of infertility in men with spinal cord injury.
Review in Nature reviews. Urology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Spinal cord stimulation: An emerging strategy for chronic pain relief after spinal cord injury.Neural regeneration research · 2026Article
- Sexual Dysfunction and Infertility in Male Patients With Spinal Cord Injury: A Narrative Review.Cureus · 2026Review
- Effects of Melissa officinalis extract in the expression of NLRP3 gene in testicular tissue and sperm parameters in the male rat model of spinal cord injury.Journal of molecular histology · 2025Article
- Advanced hydrogels: New expectation for the repair of organic erectile dysfunction.Materials today. Bio · 2023Review
- Penile Vibratory Stimulation for Semen Retrieval in Men with Spinal Cord Injury: Patient Perspectives.Research and reports in urology · 2022Review
- Spinal Cord Injury Causes Reduction ofFrontiers in neurology · 2021Article
- Hydrogen Gas: A Novel Type of Antioxidant in Modulating Sexual Organs Homeostasis.Oxidative medicine and cellular longevity · 2021Review
- Male genital sensation after spinal cord injury: a review.Translational andrology and urology · 2020Review
- Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review.Frontiers in pharmacology · 2020Review
- Chronic Spinal Cord Injury Reduces Gastrin-Releasing Peptide in the Spinal Ejaculation Generator in Male Rats.Journal of neurotrauma · 2019Article
- Impact of Immune System Activation and Vascular Impairment on Male and Female Sexual Dysfunction.Sexual medicine reviews · 2019Review
- Potential chances for natural fertility influence results of intrauterine inseminations.European journal of obstetrics & gynecology and reproductive biology: X · 2019Article
- Application of Sex Aids in Men With Sexual Dysfunction: A Review.The journal of sexual medicine · 2019Review
- Spinal cord injury and male infertility-a review of current literature, knowledge gaps, and future research.Translational andrology and urology · 2018Review
- Prevalence of parenthood in wheelchair-dependent persons with long-term spinal cord injury in the Netherlands.Spinal cord · 2018Article
- Lipid Peroxidation and Its Role in the Expression of NLRP1a and NLRP3 Genes in Testicular Tissue of Male Rats: a Model of Spinal Cord InjuryIranian biomedical journal · 2018Article
- Improvement of Sexual and Reproductive Function in Men with Spinal Cord Lesion.Acta clinica Croatica · 2018Review
- Comparison of three methods of penile vibratory stimulation for semen retrieval in men with spinal cord injury.Spinal cord · 2017Article
- Early spermatogenesis changes in traumatic complete spinal cord-injured adult patients.Spinal cord · 2017Article
- Changes in Gene Expression and Metabolism in the Testes of the Rat following Spinal Cord Injury.Journal of neurotrauma · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most men with spinal cord injury (SCI) are infertile. Erectile dysfunction, ejaculatory dysfunction and semen abnormalities contribute to the problem. Treatments for erectile dysfunction include phosphodiesterase type 5 inhibitors, intracavernous injections of alprostadil, penile prostheses, and vacuum constriction devices. In anejaculatory patients who wish to father children, semen retrieval is necessary. Penile vibratory stimulation is recommended as the first line of treatment. Patients who fail penile vibratory stimulation can be referred for electroejaculation. If this approach is not possible, prostate massage is an alternative. Surgical sperm retrieval should be considered as a last resort when other methods fail. Most men with SCI have a unique semen profile characterized by normal sperm count but abnormally low sperm motility. Scientific investigations indicate that accessory gland dysfunction and abnormal semen constituents contribute to the problem. Despite abnormalities, sperm from men with SCI can successfully induce pregnancy. In selected couples, the simple method of intravaginal insemination is a viable option. Another option is intrauterine insemination. The efficacy of intrauterine insemination increases as the total motile sperm count inseminated increases. In vitro fertilization and intracytoplasmic sperm injection are options in cases of extremely low total motile sperm count. Reproductive outcomes for SCI male factor infertility are similar to outcomes for general male factor infertility.
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Registered trials
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