Evidence map›Paper›PMID 20155624›Full record

ReviewNutrition and cancer2009

Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies.

Naghma Khan, Vaqar Mustafa Adhami, Hasan Mukhtar

Abstract readReview
In one paragraph

Review in Nutrition and cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dietary polyphenols in prevention and treatment of prostate cancer.International journal of molecular sciences · 2015
    Pooled it
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  16. Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH).Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naghma KhanDepartment of Dermatology, University of Wisconsin, Madison, Wisconsin 53706, USA.
Vaqar Mustafa Adhami
Hasan Mukhtar

Funding

The Role of JunD in Androgen-Induced Changes in Prostate Gland Redox StateP50DK065303 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI BUSHMAN, WADE A. · 2003 to 2007
$4.0M
Green Tea in Chemoprevention of Prostate CancerR01CA078809 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 1999 to 2008
$1.9M
Molecular Targets for Prevention of Prostate Cancer by Green TeaR01CA101039 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2003 to 2007
$1.6M
Pomegranate for Chemoprevention and Chemotherapy of Prostate CancerR01CA120451 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2007 to 2011
$1.4M
NCI NIH HHS R01 CA078809NCI NIH HHS R01 CA 101039NCI NIH HHS R01 CA101039NCI NIH HHS R01 CA 120451NCI NIH HHS R01 CA120451NCI NIH HHS R01 CA 78809NIDDK NIH HHS P50 DK065303
6 · The paper itself

Abstract

The prevention of prostate cancer (PCa) is a crucial medical challenge in developed countries. PCa remains surrounded by puzzles in spite of the considerable progress in research, diagnosis, and treatment. It is an ideal target for chemoprevention, as clinically significant PCa usually requires more than two decades for development. Green tea and its major constituent epigallocatechin gallate (EGCG) have been extensively studied as a potential treatment for a variety of diseases including cancer. In this review, we highlight the evidences of green tea polyphenols from preclinical and clinical studies in the chemoprevention/chemotherapy of PCa.

Indexed as

AnimalsAnticarcinogenic AgentsAntineoplastic Agents, PhytogenicAntioxidantsCatechinDisease ProgressionFlavonoidsHumansMalePhenolsPolyphenolsProstatic NeoplasmsRisk FactorsTeaAnticarcinogenic AgentsAntineoplastic Agents, PhytogenicAntioxidantsCatechinepigallocatechin gallateFlavonoidsPhenolsPolyphenolsTea

Identifiers

PMID20155624
PMCPMC2991093

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.