ReviewLangenbeck's archives of surgery2010
Solid pseudopapillary neoplasm of the pancreas--proposed algorithms for diagnosis and surgical treatment.
Review in Langenbeck's archives of surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Management and outcomes of solid pseudopapillary neoplasm of the pancreas: a systematic review.Clinical and experimental medicine · 2025Pooled it
- Malignant Solid Pseudopapillary Neoplasm of the Pancreas: An Orthogonal Analysis.Annals of surgical oncology · 2024Pooled it
- Tailored Surgical Treatment and Outcomes in Solid Pseudopapillary Neoplasms of the Pancreas: A Case Series of Five Consecutive Paradigmatic Cases.Diseases (Basel, Switzerland) · 2026Article
- Ruptured solid pseudopapillary tumor of pancreas presented as an acute abdomen: a case report.Journal of medical case reports · 2025Article
- Deep learning automatic segmentation and radiomics model for diagnosing pancreatic solid neoplasms in MRI.BMC cancer · 2025Article
- Review
- Solid pseudopapillary tumor of pancreas: A report of two cases and literature review.Radiology case reports · 2024Article
- Pregnancy Complicated With a Giant Pancreatic Tumor and Decompensation of Liver Cirrhosis: A Case Report and Literature Review.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024Article
- Potential Role for Observation in Small Solid Pseudopapillary Neoplasm (SPN).Annals of surgical oncology · 2023Article
- Perioperative safety and prognosis following parenchyma-preserving surgery for solid pseudopapillary neoplasm of the pancreas.World journal of surgical oncology · 2023Article
- Solid Pseudopapillary Neoplasms of the Pancreas: a Single-Center Experience and Review of the Literature.Journal of gastrointestinal cancer · 2022Review
- Solid pseudopapillary neoplasm of the head of the pancreas: A case report.Annals of medicine and surgery (2012) · 2021Article
- Solid-pseudopapillary neoplasm of the pancreas in a patient with familial adenomatous polyposis: a case report.Surgical case reports · 2021Article
- One size does not fit all for pancreatic cancers: A review on rare histologies and therapeutic approaches.World journal of gastrointestinal oncology · 2020Review
- Similarities and differences in guidelines for the management of pancreatic cysts.World journal of gastroenterology · 2020Review
- Differentiating benign from malignant pancreatic cysts on computed tomography.European journal of radiology open · 2020Article
- Radiomics Analysis Based on Diffusion Kurtosis Imaging and T2 Weighted Imaging for Differentiation of Pancreatic Neuroendocrine Tumors From Solid Pseudopapillary Tumors.Frontiers in oncology · 2020Article
- Clinical update on the management of pseudopapillary tumor of pancreas.World journal of gastrointestinal endoscopy · 2018Review
- Management of a Pregnancy with a Solid Pseudopapillary Neoplasm of the Pancreas.Case reports in obstetrics and gynecology · 2018Article
- Solid pseudopaillary neoplasm of the pancreas: analysis of clinicopathological and immunohistochemical features in 10 cases.International journal of clinical and experimental pathology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe incidence of solid pseudopapillary neoplasm (SPN) of the pancreas is rising. Although the evidence for proper management is accumulating, we still lack diagnostic and therapeutic guidelines. In this paper, therefore, we propose an algorithm for diagnosis and treatment of this rare type of tumor.
methodsA literature search was carried out on "Medline" and "Pubmed" databases to identify studies investigating the clinicopathologic features, pathogenesis, diagnostic, and differential diagnostic pathways, and surgical and adjuvant treatment options. Evidence from relevant published literature was completed with data of six patients treated with SPN in our institution.
resultsThis study included case series and retrospective reviews only, since no higher level of evidence exists in the relevant literature. The articles emphasized that preoperative diagnosis is desirable to set up a precise plan for surgical treatment. Further, an R0 organ-sparing resection for primary SPN and an en bloc resection of locally advanced SPN are advised, while resection of synchronous as well as metachronous distant metastases is strongly advocated for this rare type of pancreatic cancer. The role of adjuvant chemo- or radiotherapy still needs to be defined. Finally, a diagnostic and therapeutic algorithm is devised in this paper to aid proper management of SPN.
conclusionCurrent recommendations for treatment of SPN of the pancreas rely mainly on case series as single institutional experiences and retrospective reviews. Although the level of evidence is relatively low, the way of management discussed above is likely to provide an excellent prognosis in typically young patients with SPN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.