ArticleJournal of autism and developmental disorders2010
Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder.
Article in Journal of autism and developmental disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Increased Prevalence of Rare Copy Number Variants in Australian Children With Fetal Alcohol Spectrum Disorder: Experience in a State-Wide Diagnostic Service.Alcohol, clinical & experimental research · 2026Article
- A pilot study on glutamate receptor and carrier gene variants and risk of childhood autism spectrum.Metabolic brain disease · 2023Article
- Article
- A comparison of the content and nature of worries of autistic and neurotypical young people as they transition from school.Autism : the international journal of research and practice · 2023Article
- Pathology and Astrocytes in Autism.Neuropsychiatric disease and treatment · 2023Review
- Decreased number and increased activation state of astrocytes in gray and white matter of the prefrontal cortex in autism.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Genetics of glutamate and its receptors in autism spectrum disorder.Molecular psychiatry · 2022Review
- Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder.Journal of autism and developmental disorders · 2020Article
- Gene-environment interaction: New insights into perceived parenting and social anxiety among adolescents.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
- Comorbid autism spectrum disorder and anxiety disorders: a brief review.Future neurology · 2018Review
- Association between glutamate transporter gene polymorphisms and obsessive-compulsive disorder/trait empathy in a Korean population.PloS one · 2018Article
- Altered gene expression in early postnatal monoamine oxidase A knockout mice.Brain research · 2017Article
- Article
- Genetic variation in neuronal glutamate transport genes and associations with posttraumatic seizure.Epilepsia · 2016Article
- The Treatment of Anxiety in Autism Spectrum Disorder (TAASD) Study: Rationale, Design and Methods.Journal of child and family studies · 2016Article
- An update on anxiety in youth with autism spectrum disorders.Current opinion in psychiatry · 2015Review
- Developmental maturation of astrocytes and pathogenesis of neurodevelopmental disorders.Journal of neurodevelopmental disorders · 2013Article
- Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder.Translational psychiatry · 2013Article
- Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2011Article
- Gestational exposure to low dose bisphenol A alters social behavior in juvenile mice.PloS one · 2011Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Investigated association of single nucleotide polymorphism (SNP) rs301430 in glutamate transporter gene (SLC1A1) with severity of repetitive behaviors (obsessive-compulsive behaviors, tics) and anxiety in children with autism spectrum disorder (ASD). Mothers and/or teachers completed a validated DSM-IV-referenced rating scale for 67 children with autism spectrum disorder. Although analyses were not significant for repetitive behaviors, youths homozygous for the high expressing C allele had more severe anxiety than carriers of the T allele. Allelic variation in SLC1A1 may be a biomarker for or modifier of anxiety symptom severity in children with ASD, but study findings are best conceptualized as tentative pending replication with larger independent samples.
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