ReviewEuropean journal of clinical pharmacology2010
Novel strategies for the treatment of inflammatory hyperalgesia.
Review in European journal of clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 21 citations in OpenAlex.
- Anti-inflammatory and Anti-nociceptive Actions of Systemically or Locally Treated Adipose-Derived Mesenchymal Stem Cells in Experimental Inflammatory Model.Inflammation · 2015Article
- Preventive and therapeutic effects of a beta adrenoreceptor agonist, dobutamine, in carrageenan-induced inflammatory nociception in rats.Inflammation · 2014Article
- Simultaneous tissue profiling of eicosanoid and endocannabinoid lipid families in a rat model of osteoarthritis.Journal of lipid research · 2014Article
- Effects of a selective sigma 1 antagonist compound on inflammatory pain.Inflammation · 2014Article
- Molecular Docking Studies of Phytocompounds from the Phyllanthus Species as Potential Chronic Pain Modulators.Scientia pharmaceuticaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a large unmet medical need in the area of treatment of inflammatory pain initiated by tissue damage or inflammation that manifests as spontaneous pain and pain hypersensitivity (hyperalgesia).The current review focuses on the key mechanisms that produce hyperalgesia that accompanies inflammation. Also, the inflammatory mediators that interact with neurons to produce hyperalgesia are explored. As the dominant classes of analgesic drugs such as the NSAIDs and the opiates are limited by their side effects and tolerability, elucidation of the molecular mechanisms responsible for inflammatory pain provides novel opportunities for therapeutic approaches for managing inflammatory pain, with improved specificity, efficacy, and possibly with fewer toxic effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.