ArticleApplied and environmental microbiology2010
Regulation of morphogenesis and biocontrol properties in Trichoderma virens by a VELVET protein, Vel1.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed.
- Regulation of Peptaibol Profile by Velvet LAE1/VEL1 inMicroorganisms · 2026Article
- Metabolic reprogramming landscape orchestrating chlamydospore formation inFrontiers in microbiology · 2026Article
- Is heptelidic (koningic) acid a microbial hormone that regulates secondary metabolism in the biocontrol fungus Trichoderma virens?Current genetics · 2025Article
- Harnessing Trichoderma Mycoparasitism as a Tool in the Management of Soil Dwelling Plant Pathogens.Microbial ecology · 2024Review
- Beyond morphogenesis and secondary metabolism: function of Velvet proteins and LaeA in fungal pathogenesis.Applied and environmental microbiology · 2024Review
- Global regulation of fungal secondary metabolism inEngineering microbiology · 2023Article
- Transcriptome Analysis ofJournal of fungi (Basel, Switzerland) · 2023Article
- Comparative Transcriptomics Profiling of Perennial Ryegrass Infected with Wild Type or a ΔJournal of fungi (Basel, Switzerland) · 2023Article
- Role of the Global Fitness Regulator Genes on the Osmotic Tolerance Ability and Salinity Hazard Alleviation ofJournal of fungi (Basel, Switzerland) · 2022Article
- Article
- Ascomycota as a source of natural colorants.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
- The Velvet Protein UvVEA Regulates Conidiation and Chlamydospore Formation inJournal of fungi (Basel, Switzerland) · 2022Article
- Identification and Functional Analysis of a Novel Hydrophobic Protein VdHP1 from Verticillium dahliae.Microbiology spectrum · 2022Article
- Adhesion as a Focus in Trichoderma-Root Interactions.Journal of fungi (Basel, Switzerland) · 2022Review
- Review
- Co-culture of Vel1-overexpressed Trichoderma asperellum and Bacillus amyloliquefaciens: An eco-friendly strategy to hydrolyze the lignocellulose biomass in soil to enrich the soil fertility, plant growth and disease resistance.Microbial cell factories · 2021Article
- FungalBiomolecules · 2021Article
- Molecular methods unravel the biosynthetic potential ofRSC advances · 2021Review
- Transcriptome Dynamics Underlying Chlamydospore Formation inFrontiers in microbiology · 2021Article
- Gα3 subunit Thga3 positively regulates conidiation, mycoparasitism, chitinase activity, and hydrophobicity of Trichoderma harzianum.AMB Express · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycoparasitic strains of Trichoderma are applied as commercial biofungicides for control of soilborne plant pathogens. Although the majority of commercial biofungicides are Trichoderma based, chemical pesticides, which are ecological and environmental hazards, still dominate the market. This is because biofungicides are not as effective or consistent as chemical fungicides. Efforts to improve these products have been limited by a lack of understanding of the genetic regulation of biocontrol activities. In this study, using gene knockout and complementation, we identified the VELVET protein Vel1 as a key regulator of biocontrol, as well as morphogenetic traits, in Trichoderma virens, a commercial biocontrol agent. Mutants with mutations in vel1 were defective in secondary metabolism (antibiosis), mycoparasitism, and biocontrol efficacy. In nutrient-rich media they also lacked two types of spores important for survival and development of formulation products: conidia (on agar) and chlamydospores (in liquid shake cultures). These findings provide an opportunity for genetic enhancement of biocontrol and industrial strains of Trichoderma, since Vel1 is very highly conserved across three Trichoderma species.
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Registered trials
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