ReviewDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver2010
Recent advances in the regulation of cholangiocyte proliferation and function during extrahepatic cholestasis.
Review in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Review
- Species specific morphological alterations in liver tissue after biliary occlusion in rat and mouse: Similar but different.PloS one · 2022Article
- The Interplay Between Biliary Occlusion and Liver Regeneration: Repeated Regeneration Stimuli Restore Biliary Drainage by Promoting Hepatobiliary Remodeling in a Rat Model.Frontiers in surgery · 2022Article
- Protective Effects of Bee Venom-Derived Phospholipase ABiomedicines · 2021Article
- α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.Gene expression · 2018Article
- The emerging role of mast cells in liver disease.American journal of physiology. Gastrointestinal and liver physiology · 2017Review
- Apamin suppresses biliary fibrosis and activation of hepatic stellate cells.International journal of molecular medicine · 2017Article
- Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease.Laboratory investigation; a journal of technical methods and pathology · 2016Article
- Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin-1.Hepatology (Baltimore, Md.) · 2015Article
- CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB.The Journal of clinical investigation · 2015Article
- Activation of the renin-angiotensin system stimulates biliary hyperplasia during cholestasis induced by extrahepatic bile duct ligation.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- Immunohistochemical study for the origin of ductular reaction in chronic liver disease.International journal of clinical and experimental pathology · 2014Article
- Role of follicle-stimulating hormone on biliary cyst growth in autosomal dominant polycystic kidney disease.Liver international : official journal of the International Association for the Study of the Liver · 2013Article
- The dynamic biliary epithelia: molecules, pathways, and disease.Journal of hepatology · 2013Review
- Yes-associated protein regulates the hepatic response after bile duct ligation.Hepatology (Baltimore, Md.) · 2012Article
- Corrosion Cast and 3D Reconstruction of the Murine Biliary Tree After Biliary Obstruction: Quantitative Assessment and Comparison With 2D Histology.Journal of clinical and experimental hepatologyArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Bile duct epithelial cells (i.e., cholangiocytes), which line the intrahepatic biliary epithelium, are the target cells in a number of human cholestatic liver diseases (termed cholangiopathies). Cholangiocyte proliferation and death is present in virtually all human cholangiopathies. A number of recent studies have provided insights into the key mechanisms that regulate the proliferation and function of cholangiocytes during the pathogenesis of cholestatic liver diseases. In our review, we have summarised the most important of these recent studies over the past 3 years with a focus on those performed in the animal model of extrahepatic bile duct ligation. In the first part of the review, we provide relevant background on the biliary ductal system. We then proceed with a general discussion of the factors regulating biliary proliferation performed in the cholestatic animal model of bile duct ligation. Further characterisation of the factors that regulate cholangiocyte proliferation and function will help in elucidating the mechanisms regulating the pathogenesis of biliary tract diseases in humans and in devising new treatment approaches for these devastating diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.