ReviewCurrent opinion in genetics & development2010
Paramutation in maize: RNA mediated trans-generational gene silencing.
Review in Current opinion in genetics & development, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 136 citations in OpenAlex.
- Teleosts as Models for Epigenetic Inheritance.Molecular ecology · 2026Review
- Epididymal dynamics and preimplantation roles of a sperm-enriched 5' fragment of tRNA-valine.Cell reports · 2025Article
- From chromatin to crop: epigenetic innovations in bioenergy systems.Frontiers in plant science · 2025Review
- Ectopic enhancer-enhancer interactions as causal forces driving RNA-directed DNA methylation in gene regulatory regions.Plant biotechnology journal · 2024Article
- Heritable changes of epialleles near genes in maize can be triggered in the absence of CHH methylation.Plant physiology · 2024Article
- Article
- A potential candidate gene associated with the angles of the ear leaf and the second leaf above the ear leaf in maize.BMC plant biology · 2023Article
- Sperm RNA Payload: Implications for Intergenerational Epigenetic Inheritance.International journal of molecular sciences · 2023Review
- From correlation to causation: The new frontier of transgenerational epigenetic inheritance.BioEssays : news and reviews in molecular, cellular and developmental biology · 2023Article
- Review
- Soma-to-germline RNA communication.Nature reviews. Genetics · 2022Review
- Phenotypic plasticity as a facilitator of microbial evolution.Environmental epigenetics · 2022Review
- Article
- Article
- Polyploidy-associated paramutation in Arabidopsis is determined by small RNAs, temperature, and allele structure.PLoS genetics · 2021Article
- Early life lessons: The lasting effects of germline epigenetic information on organismal development.Molecular metabolism · 2020Review
- UNBRANCHED3 Expression and Inflorescence Development is Mediated by UNBRANCHED2 and the Distal Enhancer, KRN4, in Maize.PLoS genetics · 2020Article
- Molecular mechanisms of epigenetic inheritance: Possible evolutionary implications.Seminars in cell & developmental biology · 2020Review
- Transgenerational epigenetic inheritance: from phenomena to molecular mechanisms.Current opinion in neurobiology · 2019Review
- Perspectives on microRNAs and Phased Small Interfering RNAs in Maize (Plants (Basel, Switzerland) · 2019Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Paramutation involves trans-interactions between alleles or homologous sequences that establish distinct gene expression states that are heritable for generations. It was first described in maize by Alexander Brink in the 1950s, with his studies of the red1 (r1) locus. Since that time, paramutation-like phenomena have been reported in other maize genes, other plants, fungi, and animals. Paramutation can occur between endogenous genes, two transgenes or an endogenous gene, and transgene. Recent results indicate that paramutation involves RNA-mediated heritable chromatin changes and a number of genes implicated in RNAi pathways. However, not all aspects of paramutation can be explained by known mechanisms of RNAi-mediated transcriptional silencing.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.