ReviewItalian journal of pediatrics2010
"Idiopathic" mental retardation and new chromosomal abnormalities.
Review in Italian journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of central nervous system anomalies in incontinentia pigmenti.Orphanet journal of rare diseases · 2013Pooled it
- Trends and cross-country inequalities in the global burden of neurodevelopmental disorders among children aged 0-14 from 1990 to 2021.Frontiers in public health · 2025Article
- Burdens of idiopathic developmental intellectual disability attributable to lead exposure from 1990 to 2021 and projection to 2035 in China: findings from the 2021 global burden of disease study.Frontiers in public health · 2025Article
- Overexpression of miR-25 Downregulates the Expression of ROBO2 in Idiopathic Intellectual Disability.International journal of molecular sciences · 2024Article
- Karyotype analysis in children with idiopathic intellectual disability.Sudanese journal of paediatrics · 2019Article
- Screening for intellectual disability using high-resolution CMA technology in a retrospective cohort from Central Brazil.PloS one · 2014Article
- Multiplex ligation-dependant probe amplification study of children with idiopathic mental retardation in South India.Indian journal of human genetics · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental retardation is a heterogeneous condition, affecting 1-3% of general population. In the last few years, several emerging clinical entities have been described, due to the advent of newest genetic techniques, such as array Comparative Genomic Hybridization. The detection of cryptic microdeletion/microduplication abnormalities has allowed genotype-phenotype correlations, delineating recognizable syndromic conditions that are herein reviewed. With the aim to provide to Paediatricians a combined clinical and genetic approach to the child with cognitive impairment, a practical diagnostic algorithm is also illustrated. The use of microarray platforms has further reduced the percentage of "idiopathic" forms of mental retardation, previously accounted for about half of total cases. We discussed the putative pathways at the basis of remaining "pure idiopathic" forms of mental retardation, highlighting possible environmental and epigenetic mechanisms as causes of altered cognition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.