Evidence map›Paper›PMID 20151238›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2010

Enhanced definition PET for cardiac imaging.

Ludovic Le Meunier, Piotr J Slomka, Damini Dey, Amit Ramesh, Louis E J Thomson, Sean W Hayes, John D Friedman, Victor Cheng, Guido Germano, Daniel S Berman

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Impact of TOF on Brain PET With Short-LivedFrontiers in medicine · 2022
    Article
  2. Analytical quantification of aortic valve 18F-sodium fluoride PET uptake.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  3. Understanding the impact of advanced PET reconstruction in cardiac PET: The devil is in the details.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  4. Time-of-flight in cardiac PET/TC: What do we know and what we should know?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  5. The effect of time-of-flight and point spread function modeling onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  6. Comparative analysis of iterative reconstruction algorithms with resolution recovery and time of flight modeling forJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  7. Myocardial blood flow and left ventricular functional reserve in hypertrophic cardiomyopathy: aEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
  8. Review
  9. A method to assess image quality for Low-dose PET: analysis of SNR, CNR, bias and image noise.Cancer imaging : the official publication of the International Cancer Imaging Society · 2016
    Article
  10. Imaging moving heart structures with PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  11. Article
  12. Evaluation of image reconstruction algorithms encompassing Time-Of-Flight and Point Spread Function modelling for quantitative cardiac PET: phantom studies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  13. Article
  14. Impact of point spread function modeling and time-of-flight on myocardial blood flow and myocardial flow reserve measurements for rubidium-82 cardiac PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  15. Article
  16. Review
  17. Myocardial perfusion imaging with PET.Imaging in medicine · 2013
    Article
  18. Review
  19. Improvement in PET myocardial perfusion image quality and quantification with flurpiridaz F 18.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ludovic Le MeunierDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Taper Bldg, #A238, 8700 Beverly Blvd, Los Angeles, CA 90048, USA. ludovic.lemeunier@cshs.org
Piotr J Slomka
Damini Dey
Amit Ramesh
Louis E J Thomson
Sean W Hayes
John D Friedman
Victor Cheng
Guido Germano
Daniel S Berman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to determine in phantom and cardiac clinical studies the impact of a new high-resolution PET image reconstruction.

methodsA phantom with cardiac insert filled with (18)F, 14 (18)F-FDG viability studies and 15 (82)Rb perfusion studies were acquired on a Siemens Biograph-64 (4-ring). The data were reconstructed with 2D- and 3D-attenuation weighted ordered subsets expectation maximization (AWOSEM), and high-definition reconstruction (HD.PET). We calculated wall/cavity contrast, contrast-to-noise ratio (CNR), wall thickness, motion/thickening and ejection fraction.

resultsIn the phantom study, we found an increase in defect size (up to 26%), contrast (up to 48%) and CNR (1.9) with HD.PET as compared to standard techniques. The contrast increased on HD.PET images compared to 2D- and 3D-AWOSEM for viability (14.0% +/- 4.8%) and perfusion studies (7.3% +/- 4.3%) (P < .05). Average CNR increased with HD.PET by 79.4% +/- 17.1% and 68.8% +/- 3.0% in viability and perfusion studies respectively (all P < .05). Average wall thickness with HD.PET decreased in the phantom study by 1.3 +/- 0.3 mm and the viability studies by 1.9 +/- 0.7 mm but not in the perfusion studies. The functional measurements were not significantly different for any techniques.

conclusionsWe demonstrated both in phantom and patient cardiac studies that HD.PET improves image contrast, defect definition, and CNR.

Indexed as

Image EnhancementPositron-Emission TomographyFemaleFluorodeoxyglucose F18HeartHumansImage Processing, Computer-AssistedMaleMyocardial ContractionPhantoms, ImagingRadiopharmaceuticalsRubidium RadioisotopesStroke VolumeFluorodeoxyglucose F18RadiopharmaceuticalsRubidium Radioisotopes

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.