Evidence map›Paper›PMID 20151052›Full record

SynthesisThe Canadian journal of cardiology2010

The efficacy of smoking cessation therapies in cardiac patients: a meta-analysis of randomized controlled trials.

Mark J Eisenberg, Lisa M Blum, Kristian B Filion, Stephane Rinfret, Louise Pilote, Gilles Paradis, Lawrence Joseph, André Gervais, Jennifer O'Loughlin

Open access · bronzeAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in The Canadian journal of cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mark J EisenbergDivision of Cardiology, Jewish General Hospital/McGill University, 3755 Cote Ste. Catherine Road, Montreal, Quebec, Canada. mark.eisenberg@mcgill.ca
Lisa M Blum
Kristian B Filion
Stephane Rinfret
Louise Pilote
Gilles Paradis
Lawrence Joseph
André Gervais
Jennifer O'Loughlin
McGill University Health Centre · CACentre Hospitalier de l’Université de Montréal · CAJewish General Hospital · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral meta-analyses have examined the efficacy of smoking cessation therapies in the general population. However, little is known about the efficacy of these therapies in cardiac patients. Therefore, a meta-analysis of randomized controlled trials (RCTs) was performed to determine the efficacy of behavioural therapy and pharmacotherapy for smoking cessation in cardiac patients.

methodsThe medical literature was systematically reviewed to identify smoking cessation RCTs in cardiac patients. Only RCTs that reported smoking abstinence at six or 12 months were included. Smoking abstinence was examined based on the 'most rigorous criterion', defined as the most conservative outcome reported in any given RCT.

resultsEleven behavioural therapy RCTs that enrolled 2105 patients and four pharmacotherapy RCTs that enrolled 1542 patients were identified. RCTs differed in the type of behavioural therapy administered as well as the total length and duration of the intervention. RCTs differed in the type of pharmacotherapy administered (one nicotine patch RCT, one nicotine gum RCT and two bupropion RCTs). Behavioural therapy was associated with a significantly higher proportion of smoking abstinence than usual care (OR 1.97 [95% CI 1.37 to 2.85]). Pharmacotherapies were more efficacious than placebo (pooled OR 1.72 [95% CI 1.15 to 2.57]).

conclusionsBoth behavioural therapy and pharmacotherapy are more efficacious than usual care for smoking cessation in cardiac patients. The present meta-analysis highlights the need for head-to-head RCTs to identify which smoking cessation therapy is preferred in cardiac patients as well as RCTs examining the efficacy of combined behavioural and pharmacotherapies.

Indexed as

Randomized Controlled Trials as TopicAntidepressive Agents, Second-GenerationBehavior TherapyBupropionCardiovascular DiseasesHumansSmokingSmoking CessationTreatment OutcomeAntidepressive Agents, Second-GenerationBupropion

Identifiers

PMID20151052
PMCPMC2851386
OpenAlexW1984861323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.