Evidence map›Paper›PMID 20149636›Full record

ReviewCurrent opinion in structural biology2010

Virus particle maturation: insights into elegantly programmed nanomachines.

John E Johnson

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 96 citations in OpenAlex.

  1. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
    Review
  2. Review
  3. Label-free microscopy for virus infections.Microscopy (Oxford, England) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

John E JohnsonDepartment of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. jackj@scripps.edu
Scripps Research Institute · US

Funding

HIGH RESOLUTION STRUCTURAL STUDY OF DSDNA BACTERIOPHAGER01AI040101 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI JOHNSON, JOHN EMIL · 1996 to 2014
$5.2M
NIAID NIH HHS R01 AI040101NIAID NIH HHS R01-AI040101
6 · The paper itself

Abstract

Similar modes of virus maturation have been observed in dsDNA bacteriophages and the structurally related herpes viruses and some type of maturation occur in most animal viruses. Recently a variety of biophysical studies of maturation intermediates of bacteriophages P22, lambda, and HK97 have suggested an energy landscape that drives the transitions and structure-based mechanisms for its formation. Near-atomic resolution models of subunit tertiary structures in an early intermediate of bacteriophage HK97 maturation revealed a remarkable distortion of the secondary structures when compared to the mature particle. Scaffolding proteins may induce the distortion that is maintained by quaternary structure interactions following scaffold release, making the intermediate particle metastable.

Indexed as

Bacteriophage P22BacteriophagesCapsid ProteinsModels, BiologicalVirionCapsid Proteins

Identifiers

PMID20149636
PMCPMC2854226
OpenAlexW2028719074

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.