ArticleBMC genomics2010
Mapping main, epistatic and sex-specific QTL for body composition in a chicken population divergently selected for low or high growth rate.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 47 citations in OpenAlex.
- C-type natriuretic peptide regulates lipid metabolism through a NPRB-PPAR pathway in the intramuscular and subcutaneous adipocytes in chickens.Scientific reports · 2025Article
- Effect of High Dietary Iron on Fat Deposition and Gut Microbiota in Chickens.Animals : an open access journal from MDPI · 2024Article
- Genome-wide association study reveals the genetic determinism of growth traits in a Gushi-Anka FHeredity · 2021Article
- Association of the thyroid hormone responsive spot 14 alpha gene with growth-related traits in Korean native chicken.Asian-Australasian journal of animal sciences · 2020Article
- QTL Fine Mapping for Sex Determination Region in Bighead Carp (Hypophthalmichthys nobilis) and Comparison with Silver Carp (Hypophthalmichthys molitrix).Marine biotechnology (New York, N.Y.) · 2020Article
- Mapping of Quantitative Trait Loci for Growth and Carcass-Related Traits in Chickens Using a Restriction-Site Associated DNA Sequencing Method.The journal of poultry science · 2019Article
- A genome-wide association study reveals novel genomic regions and positional candidate genes for fat deposition in broiler chickens.BMC genomics · 2018Article
- Article
- Genome-wide association study of 8 carcass traits in Jinghai Yellow chickens using specific-locus amplified fragment sequencing technology.Poultry science · 2016Article
- Genome-Wide Association Study for Muscle Fat Content and Abdominal Fat Traits in Common Carp (Cyprinus carpio).PloS one · 2016Article
- Genome-Wide Linkage Analysis Identifies Loci for Physical Appearance Traits in Chickens.G3 (Bethesda, Md.) · 2015Article
- A genome scan revealed significant associations of growth traits with a major QTL and GHR2 in tilapia.Scientific reports · 2014Article
- Changes in variance explained by top SNP windows over generations for three traits in broiler chicken.Frontiers in genetics · 2014Article
- Re-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken.PloS one · 2014Article
- Genome-wide interval mapping using SNPs identifies new QTL for growth, body composition and several physiological variables in an F2 intercross between fat and lean chicken lines.Genetics, selection, evolution : GSE · 2013Article
- Overview of Genomic Insights into Chicken Growth Traits Based on Genome-Wide Association Study and microRNA Regulation.Current genomics · 2013Article
- Article
- Genetic dissection of growth traits in a Chinese indigenous × commercial broiler chicken cross.BMC genomics · 2013Article
- A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content.BMC genomics · 2012Article
- Whole genome QTL mapping for growth, meat quality and breast meat yield traits in turkey.BMC genetics · 2011Article
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Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundDelineating the genetic basis of body composition is important to agriculture and medicine. In addition, the incorporation of gene-gene interactions in the statistical model provides further insight into the genetic factors that underlie body composition traits. We used Bayesian model selection to comprehensively map main, epistatic and sex-specific QTL in an F2 reciprocal intercross between two chicken lines divergently selected for high or low growth rate.
resultsWe identified 17 QTL with main effects across 13 chromosomes and several sex-specific and sex-antagonistic QTL for breast meat yield, thigh + drumstick yield and abdominal fatness. Different sets of QTL were found for both breast muscles [Pectoralis (P) major and P. minor], which suggests that they could be controlled by different regulatory mechanisms. Significant interactions of QTL by sex allowed detection of sex-specific and sex-antagonistic QTL for body composition and abdominal fat. We found several female-specific P. major QTL and sex-antagonistic P. minor and abdominal fatness QTL. Also, several QTL on different chromosomes interact with each other to affect body composition and abdominal fatness.
conclusionsThe detection of main effects, epistasis and sex-dimorphic QTL suggest complex genetic regulation of somatic growth. An understanding of such regulatory mechanisms is key to mapping specific genes that underlie QTL controlling somatic growth in an avian model.
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