ArticleAddiction (Abingdon, England)2010
Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression.
Article in Addiction (Abingdon, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03631992 (Downshifting Sweet Preference and Added Sugar Intake During Snacking), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Downshifting Sweet Preference and Added Sugar Intake During Snacking
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years.The Cochrane database of systematic reviews · 2015Pooled it
- Oral sucrose administration to reduce pain response during immunization in 16-19-month infants: a randomized, placebo-controlled trial.European journal of pediatrics · 2014Trial
- Interplay of cultural beliefs, psychological disposition, and social milieu during childhood on development of substance use disorder by early adulthood.Experimental and clinical psychopharmacology · 2025Article
- Exploring influencing factors of healthy lifestyles in rural area among older adults with diabetes based on socioecological model.Scientific reports · 2025Article
- Weighted Family History Density of Substance Use: Influence on Participant Substance Use Onset, Duration, and Escalation.Substance abuse and rehabilitation · 2025Article
- Biological and behavioral pathways from prenatal depression to offspring cardiometabolic risk: Testing the developmental origins of health and disease hypothesis.Developmental psychology · 2024Review
- Sucrose solution for alleviating needle pain during inferior alveolar nerve block in children aged 7-10 years: a randomized clinical trial.Journal of dental anesthesia and pain medicine · 2023Article
- Exploration of the Impact of Combining Risk Phenotypes on the Likelihood of Alcohol Problems in Young Adults.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Trends in Food Preferences and Sustainable Behavior during the COVID-19 Lockdown: Evidence from Spanish Consumers.Foods (Basel, Switzerland) · 2021Article
- Prospective associations between parental substance use and youth highly processed food intake in the Fragile Families and Child Wellbeing Study.Drug and alcohol dependence · 2020Article
- Article
- Sweet taste does not modulate pain perception in adult humans.Wellcome open research · 2020Article
- Variation in the TAS2R31 bitter taste receptor gene relates to liking for the nonnutritive sweetener Acesulfame-K among children and adults.Scientific reports · 2016Article
- Psychophysical Tracking Method to Measure Taste Preferences in Children and Adults.Journal of visualized experiments : JoVE · 2016Article
- The development of sweet taste: From biology to hedonics.Reviews in endocrine & metabolic disorders · 2016Review
- Vegetable and Fruit Acceptance during Infancy: Impact of Ontogeny, Genetics, and Early Experiences.Advances in nutrition (Bethesda, Md.) · 2016Review
- The sweetness and bitterness of childhood: Insights from basic research on taste preferences.Physiology & behavior · 2015Review
- Alcohol sensory processing and its relevance for ingestion.Physiology & behavior · 2015Review
- Endophenotypes for Alcohol Use Disorder: An Update on the Field.Current addiction reports · 2015Article
- Ontogeny of taste preferences: basic biology and implications for health.The American journal of clinical nutrition · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimTo determine whether depression and family history of alcoholism are associated with heightened sweet preferences in children, before they have experienced alcohol or tobacco and at a time during the life-span when sweets are particularly salient. Design Between- and within-subject experimental study.
participantsChildren, 5-12 years old (n = 300), formed four groups based on family history of alcohol dependence up to second-degree relatives [positive (FHP) versus negative (FHN)] and depressive symptoms as determined by the Pictorial Depression Scale [depressed (PDEP) versus non-depressed (NDEP)]. MEASUREMENTS: Children were tested individually to measure sucrose preferences, sweet food liking and, for a subset of the children, the analgesic properties of sucrose versus water during the cold pressor test.
findingsThe co-occurrence of having a family history of alcoholism and self-reports of depressive symptomatology was associated significantly with a preference for a more concentrated sucrose solution, while depressive symptomatology alone was associated with greater liking for sweet-tasting foods and candies and increased pain sensitivity. Depression antagonized the analgesic properties of sucrose.
conclusionsWhile children as a group innately like sweets and feel better after eating them, the present study reveals significant contributions of family history of alcoholism and depression to this effect. Whether the heightened sweet preference and the use of sweets to alleviate depression are markers for developing alcohol-related problems or responses that are protective are important areas for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.