ReviewAnnual review of physiology2010
Circadian organization of behavior and physiology in Drosophila.
Review in Annual review of physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 250 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
250 citing papers in PubMed, 467 citations in OpenAlex.
- Article
- Article
- Review
- Peroxisomal import is circadian in glia and regulates sleep and lipid metabolism.PLoS biology · 2026Article
- Alternative 3' Polyadenylation Responses to Acute Ethanol Exposure Differ Between Drosophila Populations.Research square · 2026Article
- Metaplastic sleep regulation inbioRxiv : the preprint server for biology · 2026Article
- Genomic Signatures of Speciation in Butterflies.Systematic biology · 2026Article
- Brain Transcriptomics Across Diverse Sleep-Wake Manipulations Reveals Multiple Homeostatic Pathways inbioRxiv : the preprint server for biology · 2026Article
- Non-visual opsins and their role in circadian photoentrainment.Eye and vision (London, England) · 2026Review
- Remote and partial clocks expand the circadian neuronal network, driving widespread molecular rhythmicity inbioRxiv : the preprint server for biology · 2025Article
- Article
- Identification of Distinct Topological Structures From High-Dimensional Data.bioRxiv : the preprint server for biology · 2025Article
- A rapid and dynamic role for FMRP in the plasticity of adult neurons.Nature communications · 2025Article
- A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Persistent viral infections impact key biological traits in Drosophila melanogaster.PLoS biology · 2025Article
- Circadian Biology in Parasites: Beyond Known Mechanisms.Annual review of microbiology · 2025Review
- Role of d-serine in intestinal ROS accumulation after sleep deprivation.Science advances · 2025Article
- Anti-Müllerian hormone signalling sustains circadian homeostasis in zebrafish.Nature communications · 2025Article
- The cell-intrinsic circadian clock is dispensable for lateral posterior clock neuron regulation ofNeurobiology of sleep and circadian rhythms · 2025Article
- Molecular basis of circadian rhythm divergence between diurnal and nocturnal lepidoperans.iScience · 2025Article
190 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Circadian clocks organize behavior and physiology to adapt to daily environmental cycles. Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely conserved molecular gears of these 24-h timers. Yet much less is known about how these cell-autonomous clocks confer temporal information to modulate cellular functions. Here we discuss our current knowledge of circadian clock function in Drosophila, providing an overview of the molecular underpinnings of circadian clocks. We then describe the neural network important for circadian rhythms of locomotor activity, including how these molecular clocks might influence neuronal function. Finally, we address a range of behaviors and physiological systems regulated by circadian clocks, including discussion of specific peripheral oscillators and key molecular effectors where they have been described. These studies reveal a remarkable complexity to circadian pathways in this "simple" model organism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.