Evidence map›Paper›PMID 20148317›Full record

ReviewStem cell reviews and reports2010

ATP dependent chromatin remodeling enzymes in embryonic stem cells.

Srinivas Vinod Saladi, Ivana L de la Serna

Open access · greenAbstract readReview
In one paragraph

Review in Stem cell reviews and reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Chromatin regulation and dynamics in stem cells.Current topics in developmental biology · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Establishing pluripotency in early development.Biochimica et biophysica acta · 2015
    Review
  13. Article
  14. Article
  15. SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma.Critical reviews in eukaryotic gene expression · 2014
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Epigenetic landscape of pluripotent stem cells.Antioxidants & redox signaling · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Srinivas Vinod SaladiDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine, Block Health Sciences Building, Mail Stop 1010, 3035 Arlington Avenue, Toledo, OH, 43614, USA.
Ivana L de la Serna
University of Toledo · US

Funding

Chromatin Remodeling in UVR Induced MelanogenesisK22ES012981 · NIEHS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI DE LA SERNA, IVANA L · 2005 to 2007
$317k
NIEHS NIH HHS K22 ES012981
6 · The paper itself

Abstract

Embryonic stem (ES) cells are pluripotent cells that can self renew or be induced to differentiate into multiple cell lineages, and thus have the potential to be utilized in regenerative medicine. Key pluripotency specific factors (Oct 4/Sox2/Nanog/Klf4) maintain the pluripotent state by activating expression of pluripotency specific genes and by inhibiting the expression of developmental regulators. Pluripotent ES cells are distinguished from differentiated cells by a specialized chromatin state that is required to epigenetically regulate the ES cell phenotype. Recent studies show that in addition to pluripotency specific factors, chromatin remodeling enzymes play an important role in regulating ES cell chromatin and the capacity to self-renew and to differentiate. Here we review recent studies that delineate the role of ATP dependent chromatin remodeling enzymes in regulating ES cell chromatin structure.

Indexed as

Chromatin Assembly and DisassemblyEpigenesis, GeneticAdenosine TriphosphatasesAdenosine TriphosphateAnimalsCell DifferentiationCell LineageCell ProliferationChromosomal Proteins, Non-HistoneDNA HelicasesEmbryonic Stem CellsGene Expression Regulation, DevelopmentalGenotypeHistone AcetyltransferasesHumansKruppel-Like Factor 4Adenosine TriphosphatasesAdenosine TriphosphateChromosomal Proteins, Non-HistoneDNA HelicasesHistone AcetyltransferasesISWI proteinKLF4 protein, humanKruppel-Like Factor 4SWI-SNF-B chromatin-remodeling complexTranscription Factors

Identifiers

PMID20148317
PMCPMC2862992
OpenAlexW2041832287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.