ArticleBMC genomics2010
Distinct, ecotype-specific genome and proteome signatures in the marine cyanobacteria Prochlorococcus.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- Unbiased Estimate of Synonymous and Nonsynonymous Substitution Rates with Nonstationary Base Composition.Molecular biology and evolution · 2018Article
- Transmission in the Origins of Bacterial Diversity, From Ecotypes to Phyla.Microbiology spectrum · 2017Article
- Excess of non-conservative amino acid changes in marine bacterioplankton lineages with reduced genomes.Nature microbiology · 2017Article
- Evolutionary Dynamics of Chloroplast Genomes in Low Light: A Case Study of the Endolithic Green Alga Ostreobium quekettii.Genome biology and evolution · 2016Article
- Inferring Speciation Processes from Patterns of Natural Variation in Microbial Genomes.Systematic biology · 2015Article
- Divergences in gene repertoire among the reference Prevotella genomes derived from distinct body sites of human.BMC genomics · 2015Article
- Reductive genome evolution at both ends of the bacterial population size spectrum.Nature reviews. Microbiology · 2014Article
- Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria.Frontiers in genetics · 2014Review
- Article
- A tribute to disorder in the genome of the bloom-forming freshwater cyanobacterium Microcystis aeruginosa.PloS one · 2013Article
- Microbial lifestyle and genome signatures.Current genomics · 2012Article
- Estimating genotypic richness and proportion of identical multi-locus genotypes in aquatic microalgal populations.Journal of plankton researchArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe marine cyanobacterium Prochlorococcus marinus, having multiple ecotypes of distinct genotypic/phenotypic traits and being the first documented example of genome shrinkage in free-living organisms, offers an ideal system for studying niche-driven molecular micro-diversity in closely related microbes. The present study, through an extensive comparative analysis of various genomic/proteomic features of 6 high light (HL) and 6 low light (LL) adapted strains, makes an attempt to identify molecular determinants associated with their vertical niche partitioning.
resultsPronounced strand-specific asymmetry in synonymous codon usage is observed exclusively in LL strains. Distinct dinucleotide abundance profiles are exhibited by 2 LL strains with larger genomes and G+C-content approximately 50% (group LLa), 4 LL strains having reduced genomes and G+C-content approximately 35-37% (group LLb), and 6 HL strains. Taking into account the emergence of LLa, LLb and HL strains (based on 16S rRNA phylogeny), a gradual increase in average aromaticity, pI values and beta- & coil-forming propensities and a decrease in mean hydrophobicity, instability indices and helix-forming propensities of core proteins are observed. Greater variations in orthologous gene repertoire are found between LLa and LLb strains, while higher number of positively selected genes exist between LL and HL strains.
conclusionStrains of different Prochlorococcus groups are characterized by distinct compositional, physicochemical and structural traits that are not mere remnants of a continuous genetic drift, but are potential outcomes of a grand scheme of niche-oriented stepwise diversification, that might have driven them chronologically towards greater stability/fidelity and invoked upon them a special ability to inhabit diverse oceanic environments.
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